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GenomicsTE-associated chromatin variation in mice livers
Chromatin accessibility is a hallmark of active regulatory function in the genome and variation of chromatin accessibility across individuals has been shown to contribute to complex traits and disease susceptibility. However, the mechanisms responsible for chromatin variation among different individ...
ORGANISM(S): Mus musculus 
2016-07-14 | E-GEOD-75770 | biostudies-arrayexpress
TranscriptomicsGenetic regulation of human adipose microRNA expression and its consequences for metabolic traits
The genetics of messenger RNA expression has been extensively studied in humans and other organisms, but little is known about genetic factors contributing to microRNA (miRNA) expression. We examined natural variation of miRNA expression in adipose tissue in a population of 200 men who have been car...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-45159 | biostudies-arrayexpress
UnknownIsoproterenol-Induced Cardiac Diastolic Dysfunction in Mice: A Systems Genetics Analysis.
Not available
S-EPMC6684968 | biostudies-literature
UnknownDNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains.
Not available
S-EPMC6933503 | biostudies-literature
TranscriptomicsDiet-induced chromatin remodeling in mice livers
The tissue-specific packaging of the genome into the nucleus through chromatin is fundamentally involved in gene regulation, and aberrant modifications to chromatin are a hallmark of many diseases. We show here that a high fat (HF) diet leads to substantial chromatin remodeling in the livers of C57B...
ORGANISM(S): Mus musculus 
2014-07-17 | E-GEOD-55581 | biostudies-arrayexpress
MetabolomicsRed-Fleshed Apple Anthocyanin Extracts Attenuate Male Reproductive System Dysfunction Caused by Busulfan in Mice (Mouse blood plasma; UPLC-MS/MS assays)

In this research, we analyzed the effect of oral administration of red-fleshed apple anthocyanin extract (RAAE) on busulfan-treated mice. At first, we showed that the most abundant component in RAAE was cyanidin 3-O-galactoside. To determine the effect of RAAE, mice were divided into control and ...

2021-06-07 | MTBLS2782 | MetaboLights
TranscriptomicsExpression profiling of Adipose tissue from (C57BL/6J X C3H/HeJ)F2 mice on ApoE null backgrounds
The (C57BL/6J X C3H/HeJ)F2 intercross consists of 334 animals of both sexes. All are ApoE null and received a high fat Western diet from 8-24 weeks of age. Adipose from 295 F2 female and male mice (animals fed a high fat "Western" diet from 8-24 weeks of age.) derived from C57BL/6J and C3H...
ORGANISM(S): Mus musculus 
2006-07-07 | E-GEOD-3086 | biostudies-arrayexpress
UnknownGenetic network identifies novel pathways contributing to atherosclerosis susceptibility in the innominate artery.
Not available
S-EPMC4142055 | biostudies-literature
UnknownMetabolomics, Genetics, and Environmental Factors: Intersecting Paths in Abdominal Aortic Aneurysm.
Not available
S-EPMC11855682 | biostudies-literature
UnknownGene expression analyses of mouse aortic endothelium in response to atherogenic stimuli.
Not available
S-EPMC4105212 | biostudies-literature
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