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TranscriptomicsEcdysone Response Timecourse in Kc Cells
Kc167 Cells were plated at 0.5x106/ml and grown at 23.50C. They were treated with 20-HE (Sigma) at a final concentration of 5x10-7M. The reference sample was total RNA isolated at 0 hr. after treatment. The experimental samples were total RNA isolated from cells treated for 1, 3, 6, 12, 24, and 48 h...
ORGANISM(S): Drosophila melanogaster 
2008-06-12 | E-GEOD-11625 | biostudies-arrayexpress
TranscriptomicsConcordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study
Background: Genome-wide transcriptome profiling generated by microarray and RNA-Seq often provides deregulated genes or pathways applicable only to larger cohort. On the other hand, individualized interpretation of transcriptomes is increasely pursued to improve diagnosis, prognosis, and patient tre...
ORGANISM(S): Homo sapiens 
2013-11-20 | E-GEOD-52493 | biostudies-arrayexpress
TranscriptomicsOryza sativa Transcriptome or Gene expression
The transcriptomes of resistant BPH15 introgression line and the susceptible recipient line were analyzed using high-throughput RNA sequencing. In total, 2,914 differentially expressed genes (DEGs) were identified. BPH-responsive transcript profiles were distinct between resistant and susceptible pl...
ORGANISM(S): Oryza sativa 
2014-07-28 | E-MTAB-4293 | biostudies-arrayexpress
TranscriptomicsDrosophila Ecdysone Receptor Study
We used the DamID method to systematically identify the binding sites of Ecdysone Receptor and its heterodimeric partner USP across the whole genome in Drosophila Kc cells. We find that the EcR sites are a subset of the USP sites and that only a proportion are ecdysone regulated from an accompanying...
ORGANISM(S): Drosophila melanogaster 
2008-05-01 | E-GEOD-9156 | biostudies-arrayexpress
ProteomicsIdentification of ubiquitination site in BCL-XL after PROTAC DT2216 treatment
The availability of a suitable lysine for PROTAC-mediated ubiquitination can also determine the degradative ability of a protein target and the selectivity of a PROTAC. PROTAC DT2216 selectively triggers ubiquitination and degradation of BCL-XL. In this study, we identify K87 is the key ubiquitinate...
ORGANISM(S): Homo sapiens (Human) 
2019-10-08 | PXD015454 | Pride
Bcl-xl Ubiquitination site K87 Protac Dt2216 
ProteomicsLC-MSMS measurements of paired human lung tumor/tumor-free tissues with serial dilutions
This dataset is included as one of the benchmarking dataset in the manuscript "msBayesImpute: A Versatile Framework for Addressing Missing Values in Biomedical Mass Spectrometry Proteomics Data" by He et al (https://www.biorxiv.org/content/10.1101/2025.10.02.679746v1). To better recapture the missin...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD077257 | Pride
Human Lc-msms Serial dilution Lung 
MetabolomicsQuantitative metabolomic analysis of changes in the lens and aqueous humor under development of age-related nuclear cataract

INTRODUCTION: Metabolites are essential for the proper functioning of the eye lens, they either enter the lens from the aqueous humor (AH), or are synthesized in the lens epithelium. Antioxidants, osmolytes and UV filters are especially important for the lens protection, and thei...

2022-11-07 | MTBLS740 | MetaboLights
UnknownLiver volume based prediction model for patients with hepatitis B virus-related acute-on-chronic liver failure.
Not available
S-EPMC10078645 | biostudies-literature
UnknownDelayed presentation of acute coronary syndrome with mechanical complication during COVID-19 pandemic: a case report.
Not available
S-EPMC7953974 | biostudies-literature
UnknownTimely expression and activation of YAP1 in granulosa cells is essential for ovarian follicle development.
Not available
S-EPMC6704445 | biostudies-literature
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