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TranscriptomicsSingle-cell RNAseq and scTCRseq of human CD8 T cells from blood and skin compartments in Dengue patients
Using a skin-blister induction model established for dengue, we investigated the transcriptional signatures and TCR repertoire of matched CD8 T cells in skin and blood samples
ORGANISM(S): Homo sapiens 
2026-04-14 | E-MTAB-16332 | biostudies-arrayexpress
TranscriptomicsVDJ-sequencing of fetal skin
We profiled prenatal human skin using single cell multiomic technologies to investigate the cellular and molecular changes across gestation. This dataset includes TCR transcriptomic data from single cell TCR sequencing using the 10x Genomics 5’ V(D)J Immune receptor profiling kits.
ORGANISM(S): Homo sapiens 
2024-06-04 | E-MTAB-13065 | biostudies-arrayexpress
TranscriptomicsGene expression data from mouse hemopoietic stem cells (LSKs), promyelocytes, myelocytes and granulocytes.
Differentiation of hemopoietic stem cells into granulocytes is characterized by distinct changes in the transcriptome. We analyzed mRNA expression in primary murine myeloid cells at four successive stages of hemopoietic differentiation; Lin- Sca1+ cKit+ stem/progenitor cells (LSKs), promyelocytes, m...
ORGANISM(S): Mus musculus 
2014-05-14 | E-GEOD-57622 | biostudies-arrayexpress
TranscriptomicsSex differences in the translatome of Drosophila fruitless-expressing neurons that underlie reproductive behaviors
Adult reproductive behaviors in Drosophila melanogaster males and females are vastly different. Yet, neurons that express sex-specifically spliced fruitless transcripts (fru P1) underlie these behaviors in both sexes. How the same set of neurons can drive such different behaviors is an important an...
ORGANISM(S): Drosophila melanogaster 
2015-09-01 | E-GEOD-67743 | biostudies-arrayexpress
TranscriptomicsCotranslational signal independent SRP preloading during membrane targeting
Cotranslational targeting into the endoplasmic reticulum (ER) by the Signal Recognition Particle (SRP) is a key event determining polypeptide fate in eukaryotic cells. Here, we globally define the principles and mechanisms of SRP binding and ER targeting in vivo. Cotranslational targeting through SR...
ORGANISM(S): Saccharomyces cerevisiae 
2016-08-03 | E-GEOD-74393 | biostudies-arrayexpress
Genomicsena-DATASET-DKFZ-IBIOS-29-08-2014-08:27:40:831-1015 - samples
Whole-exome sequencing of a chronic lymphocytic leukemia (CLL) developed during vemurafenib treatment of a patient with malignant melanoma. Peripheral blood mononuclear cells were separated by Ficoll gradient centrifugation. DNA was extracted from highly purified (>97%) CD19+CD5+ cells obtained from...
EGAD00001000997 | EGA
GenomicsChIP-Seq analysis of PU.1, BATF, and JunB in murine BMDCs
Purpose: The purpose of this study is to identify the genome-wide binding sites for IRF4 interaction partners PU.1, BATF, and JunB in dendritic cells. These ChIP-seq data were integrated with gene expression analysis in IRF4-sufficient and -deficient BMDCs in order to assemble an IRF4 gene regulator...
ORGANISM(S): Mus musculus 
2013-12-22 | E-GEOD-52772 | biostudies-arrayexpress
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