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MetabolomicsDesorption electrospray ionisation mass spectrometry imaging of esophageal lymph mode metastases
Lymph node metastases (LNM) and primary tumour samples were analysed using desorption electrospray ionisation mass spectrometry imaging (DESI MSI). Current assessment of LNM depends on subjective histopathological assessment, whereas analysis by DESI MSI permits an entirely objective assessment. The...
2017-01-10 | MTBLS385 | MetaboLights
TranscriptomicsGene Expression Profiling of Fixed Tissues of Lymph Node Metastasis in Hepatocellular Carcinoma
RNA was extracted from formalin-fixed specimens of paired intratumoral and peritumoral tissues of patients with lymph node-positive (n=20) or negative (n=20) HCC. A cDNA-mediated annealing, selection, extension, and ligation assay was performed with an array of 502 known cancer-related genes to iden...
ORGANISM(S): Homo sapiens 
2011-08-03 | E-GEOD-28248 | biostudies-arrayexpress
ProteomicsO-GlcNAc proteome of invasive ductal breast carcinomas
O-GlcNAc proteins in LNM and non-LNM breast tumors of IDCs were identified by using the strategy of chemo-enzymatic labeling in combination with click chemistry and LC-MS/MS.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080753 | MassIVE
ProteomicsAltered N-linked Glycosylation in Endometrial Cancer
It has been recognised for a long time that cell surface glycans plays a vital role in the biological process and their altered form can lead to cancer. However, the molecular details and regulatory mechanism between the glycans and cancer is yet not clear. Over the past decade mass spectrometry-bas...
ORGANISM(S): Homo sapiens (Human) 
2020-11-27 | PXD019425 | Pride
Biomarker Lymph node metastasis Endometrial cancer Glycan imaging 
GenomicsDifferential expression of miRNAs in plasma exosomes between ESCC patients with lymph node metastasis(LNM+) and those without lymph node metastasis(LNM-)
Differential expression of miRNAs in plasma exosomes between ESCC patients with lymph node metastasis(LNM+) and those without lymph node metastasis(LNM-)
PRJNA884661 | ENA
ProteomicsThe Proteomic Fingerprint of Prostate Cancer in Primary Tumors and Recurrent Lymph Node Metastases
We performed a quantitative proteome comparison on formalin-fixed paraffin embedded (FFPE) tissue of metastasized and non-metastasized primary prostate cancer (PCa) and on recurrent lymph node metastases. Comparing these three sample groups, we aimed to identify proteins, that might potentially prom...
ORGANISM(S): Homo sapiens (Human) 
2017-12-19 | PXD005833 | Pride
Lymph node metastases Shotgun proteomics Immunohistochemistry Prostate cancer Label free 
ProteomicsProteomics Characteristics Reveal the Risk of T1 Colorectal Cancer Metastasis to Lymph Nodes
The presence of lymph node metastasis (LNM) affects treatment strategy decisions in T1NxM0 colorectal cancer (CRC), but the currently used clinicopathological-based risk stratification cannot be used to accurately predict LNM. In this study, we established a model for predicting LNM and explored the...
ORGANISM(S): Homo Sapiens 
2023-04-12 | PXD041476 |
GenomicsExpression profiles for lymph node metastasis in I-III colorectal cancer
Expression profiles for lymph node metastasis in I-III colorectal cancer
PRJNA730414 | ENA
GenomicsEvolutionary trajectories and clonal migration underlying tumor progression and lymph node metastasis in resectable lung cancer
In this prospective study, targeted deep sequencing was performed on a total of 160 primary tumors (474 regions) and 112 lymph nodes from 125 patients with stage I-III lung cancer (LuCaTH). Progressive evolution at clonal divergence scale was observed while specific driver events were positively sel...
EGAS00001005242 | EGA
TranscriptomicsDNA methylation analysis of melanoma progression to brain metastasis
Melanoma is one of the most aggressive and treatment-resistant cancers. It represents the most life-threatening neoplasm of the skin, and its incidence has been increasing for the last three decades. Melanoma evolves from the local transformation of melanocytes to primary tumors, which can metastasi...
ORGANISM(S): Homo sapiens 
2013-09-19 | E-GEOD-44661 | biostudies-arrayexpress
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