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TranscriptomicsGene expression in PLN vs. ILN or MLN in mice
Normal gene expression in pancreatic lymph nodes compared to inguinal or mesenteric lymph nodes across different strains of mice (BALB/c, FVB, NOD, NOD.B10). Lymph nodes were excised from 12 wk old female mice (5 mice per group), and total RNA was extracted for dual dye microarray analysis.
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-15748 | biostudies-arrayexpress
TranscriptomicsLymphoid tissue specific homing of bone marrow-derived dendritic cells
Because of their potent immunoregulatory capacity, dendritic cells (DCs) have been exploited as therapeutic tools to boost immune responses against tumors or pathogens, or dampen autoimmune or allergic responses. Murine bone marrow-derived DCs (BM-DCs) are the closest known equivalent of the blood m...
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-15784 | biostudies-arrayexpress
TranscriptomicsLymph nodes with follicular lymphoma or reactive hyperplasia
Comparison of gene expression profiles of follicular lymphoma vs. reactive lymph nodes. 8 cases of follicular lymphoma; 5 cases of reactive lymph nodes.
ORGANISM(S): Homo sapiens 
2011-09-26 | E-GEOD-14214 | biostudies-arrayexpress
TranscriptomicsSGEV_LRS
Comparison of genomic expression profiles in the mesenteric lymph nodes of naturally scrapie infected (clinical and preclinical stages) and control sheep. Expression profiles comparison of 7 clinical and 4 preclinical naturally scrapie infected sheep and 6 controls.
ORGANISM(S): Ovis aries 
2013-10-29 | E-MTAB-1346 | biostudies-arrayexpress
TranscriptomicsGenes regulated by T cell and B cell derived TNF in naive lymph nodes
We present a RNA microarray analysis of RNA`s extracted from naive mesenterial lymph nodes of mice with specific inactivation of tumor necrosis factor only in B cells (B-TNf mice) or in T- and B-cells (TB-TNF mice). Several genes are cooperatively regulated by T cell derived and B cell derived TNF ...
ORGANISM(S): Mus musculus 
2010-12-07 | E-GEOD-8610 | biostudies-arrayexpress
TranscriptomicsImmune and tumor cell gene expression from node positive and node negative breast cancers' primary tumor, lymph nodes and peripheral blood
Analysis of purified immune and breast tumor cells from three major compartments where cancer and immune cells interact: primary tumor, tumor draining lymph nodes (tumor invaded or tumor free), and peripheral blood. The results suggests that node-positive patients’ immune regulation and functionali...
ORGANISM(S): Homo sapiens 
2013-01-11 | E-GEOD-41986 | biostudies-arrayexpress
TranscriptomicsRNA-seq of total lymph node cells from inducible ll7 gene deletion mice
Il7fx/KO Rosa26CreERT2 mice (samples 4, 5 and 6) and CreERT –ve littermate controls (samples 1, 2 and 3) were treated with tamoxifen for five days. Three weeks later, RNA was isolated from total lymph nodes of individual mice and gene expression determined by RNAseq.
ORGANISM(S): Mus musculus 
2018-02-16 | E-MTAB-6451 | biostudies-arrayexpress
TranscriptomicsGene expression in the pancreatic lymph node of Deaf1 knock out mice vs. BALB/c controls
A microarray study performed in the pancreatic lymph nodes of Deaf1 knock-out and BALB/c control mice to identify genes that are regulated by the transcriptional regulator Deaf1. These experiments constitute a portion of the study described below: Abstract: Type 1diabetes (T1D) can result from a b...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-13163 | biostudies-arrayexpress
TranscriptomicsGene expression in GLN versus PDLN in NOD mice
Comparison of the gene expression in the two pancreatic lymph nodes: gastric lymph node (GLN) and pancreatico-duodenal lymph node (PDLN) in NOD mice. The analysis was done in an attempt to explain the preferential homing of bone marrow-derived dendritic cells to the GLN after intravenous injection. ...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-15753 | biostudies-arrayexpress
TranscriptomicsDKK1 expression is down-regulated in the lymph node pre-metastatic niche in esophageal cancer
Lymph node metastasis is a poor prognosis indicator in esophageal cancer. Although tumor spreading currently forms the main basis for therapy selection, the molecular mechanisms underlying the metastatic pathway remain insufficiently understood. Several studies aimed to investigate these mechanisms ...
ORGANISM(S): Homo sapiens 
2015-05-18 | E-GEOD-51021 | biostudies-arrayexpress
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