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GenomicsCpG islands recruit a histone H3 lysine 36 demethylase
This SuperSeries is composed of the following subset Series: GSE18588: CpG islands recruit a histone H3 lysine 36 demethylase [Illumina sequencing data] GSE21201: CpG islands recruit a histone H3 lysine 36 demethylase [Agilent data] Refer to individual Series
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-21202 | biostudies-arrayexpress
MetabolomicsDeletion of the diabetes candidate gene Slc16a13 in mice
Not available
ORGANISM(S): Mus musculus 
ST001643 | MetabolomicsWorkbench
MetabolomicsAmino Acid Quantifcation of obese patients on a 16 week caloric restriction from Plasma
Not available
ORGANISM(S): Homo sapiens 
ST000483 | MetabolomicsWorkbench
ProteomicsDe novo mutations of MSL3 cause a novel X-linked syndrome due to impaired histone H4 lysine 16 acetylation
Epigenetic regulation by histone acetylation plays a key role in cellular homeostasis and its misregulation is associated with human disease. Histone 4 Lysine 16 acetylation (H4K16ac) serves a unique role amongst the many histone modifications as it directly affects chromatin structure1. The Male Sp...
ORGANISM(S): Homo sapiens (Human) 
2018-09-18 | PXD009317 | Pride
X-linked syndrome Acetylation Histone h4 Msl3 Lysine 16 
MetabolomicsAmino Acid Quantifcation of obese patients on a 16 week caloric restriction from muscle biopsy
Not available
ORGANISM(S): Homo sapiens 
ST000484 | MetabolomicsWorkbench
ProteomicsChemical proteomics profiling of N-terminal and lysine acetyltransferases
Acetylation of amino groups is a prevalent protein modification in all kingdoms of life. Acetyl groups are transferred from Coenzyme A (CoA) to protein N-termini and lysine side chains by N-terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs), respectively. Building on lysine-CoA ...
ORGANISM(S): Homo Sapiens (human) 
2021-04-14 | PXD018544 | JPOST Repository
TranscriptomicsNSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming [TKO]
NSD2 (also named MMSET and WHSC1) is a histone lysine methyltransferase that is implicated in diverse diseases and commonly overexpressed in multiple myeloma due to a recurrent t(4;14) chromosomal translocation. However, the precise catalytic activity of NSD2 is obscure, preventing progress in unde...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-29148 | biostudies-arrayexpress
ProteomicsInvestigating peptide-Coenzyme A-conjugates as chemical probes for proteomic profiling of N-terminal and lysine acetyltransferases
Acetyl groups are transferred from Acetyl-Coenzyme A (Ac-CoA) to protein N-termini and lysine side chains by N-terminal acetyltransferases (NATs) and lysine acetyltransferases (KATs), respectively. Building on lysine-CoA conjugates as KAT probes, we have synthesized peptide probes with CoA conjugate...
ORGANISM(S): Homo Sapiens (human) 
2022-05-02 | PXD032957 | JPOST Repository
GenomicsExpanding the CTD code: methylation of non-consensus Lysine residues marks early transcription in mammalian cells
Dynamic post-translational modification of RNA polymerase II (RNAPII) coordinates the co-transcriptional recruitment of enzymatic complexes that regulate chromatin states and co-transcriptional processing of nascent RNA. Extensive phosphorylation of serine residues occurs at the structurally-disorde...
ORGANISM(S): Mus musculus 
2015-12-22 | E-GEOD-72876 | biostudies-arrayexpress
TranscriptomicsCpG islands recruit a histone H3 lysine 36 demethylase [Agilent data]
Transcription factors that bind small DNA motifs embedded in promoters play a central role in controlling gene expression. However, in addition to these elements, up to 70% of genes in higher eukaryotes also have high levels of non-methylated cytosine/guanine base pairs (CpGs) surrounding promoters ...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-21201 | biostudies-arrayexpress
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