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ProteomicsSystematic analysis of the lysine succinylome in the model medicinal mushroom Ganoderma lucidum
Ganoderma lucidum, one of the best-known medicinal mushrooms in the world, produces more than 400 different bioactive compounds. By the combination of affinity enrichment and high-resolution LC-MS/MS analysis, large-scale lysine succinylome analysis was performed. Altogether, 742 lysine succinylatio...
ORGANISM(S): Ganoderma lucidum 
2019-07-25 | PXD013954 | Pride
Lc-ms/ms Ganoderma lucidum Lysine succinylome 
ProteomicsProteome-wide lysine succinylome profiling and comprehensive analysis of protein lysine co-modification in developing rice seeds
Lysine succinylation has been recognized as a post-translational modification (PTM) in recent years. It is plausible that succinylation may have a vaster functional impact than acetylation due to bulkier structural changes and greater charge differences on the modified lysine residue. Currently, how...
ORGANISM(S): Oryza sativa (Rice) 
2019-09-09 | PXD013664 | Pride
Post-translational modification  lysine succinylation  succinylome  rice  storage nutrient  seeds 
ProteomicsQuantitative analysis of the succinylome in the thyroid tissue of high fat diet induced hypothyroxinemia in rats
Background Hypothyroidism is a common disease, and its molecular mechanism still needs further investigation. Succinylation, as a newly identified protein posttranslational modification, is found to be involved in various metabolisms and cellular processes. In the present study, we performed quantit...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-08 | PXD012814 | Pride
Rat Hypothyroxinemia Succinylome 
ProteomicsIdentification of lysine succinylome and acetylome in vancomycin-intermediate Staphylococcus aureus XN108
In this study, we detected the first lysine succinylome and acetylome in a vancomycin-intermediate S. aureus (VISA) strain, XN108.Furthermore,Comparative analysis of the protein succinylation and acetylation between XN108-ΔcobB and XN108-WT strain was conducted on the basis of quantitative detection...
ORGANISM(S): Staphylococcus aureus 
2022-11-09 | PXD033341 | Pride
Post-translational modification  staphylococcus aureus visa  succinylation  acetylation sacobb. 
ProteomicsProteome, acetylome and succinylome analysis of pCAR1-free and pCAR1-harbouring Pseudomonas putida KT2440
The impact of the conjugative plasmid pCAR1, which is involved in carbazole degradation, on the proteome, acetylome, and succinylome of host Pseudomonas putida KT2440 was investigated using a stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative analysis.
ORGANISM(S): Pseudomonas putida KT2440 
2018-09-24 | PXD007089 | Pride
Lc-msms Silac Pcar1 Pseudomonas putida kt2440 
ProteomicsProteome, acetylome and succinylome analysis of pCAR1-free and pCAR1-harbouring Pseudomonas putida KT2440 (2)
The impact of the conjugative plasmid pCAR1, which is involved in carbazole degradation, on the proteome, acetylome, and succinylome of host Pseudomonas putida KT2440 was investigated using a stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative analysis.
ORGANISM(S): Pseudomonas putida KT2440 
2018-11-22 | PXD007090 | Pride
Lc-msms Silac Pcar1 Pseudomonas putida kt2440 
UnknownSIRT5 regulates the mitochondrial lysine succinylome and metabolic networks.
Not available
S-EPMC4105152 | biostudies-literature
UnknownSystematic analysis of the lysine succinylome in the model medicinal mushroom Ganoderma lucidum.
Not available
S-EPMC6636155 | biostudies-literature
ProteomicsSuccinylome-controlled antibiotic resistance in MRSA - Succinylome
A sucC and a sucD mutant from the Nebraska Transposon Mutant Library (NTML, Strain NE569 and NE1770) were found to be susceptible to cefoxitin and oxacillin when other mutations in TCA cycle genes did not affect their resistance to these antibiotics. The SucC strain (Strain NE569) accumulated Succin...
ORGANISM(S): Staphylococcus Aureus (ncbitaxon:1280) 
2021-03-02 | MSV000086971 | MassIVE
ProteomicsSuccinylome analysis reveals the involvement of lysine succinylation in extreme resistance of Deinococcus radiodurans
Increasing evidences showing that succinylation of lysine residue mainly regulates enzymes involved in the carbon metabolism pathway, both in prokaryotic and eukaryotic cells. Deinococcus radiodurans is one of the most radioresistant organisms on earth, which is famous for its robust resistance. A m...
ORGANISM(S): Deinococcus radiodurans 
2021-04-26 | PXD012149 | Pride
Succinylome  succinylation  dna repair  nucleic acid binding  posttranslational modification 
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