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MetabolomicsMetabolome of Streptomyces sp. HU2014

HU2014 was inoculated into an optimized medium containing dextrin (39.59 g/L), yeast extract (8.52 g/L), and KNO3 (2.49 g/L), with the initial pH adjusted to 7.0–7.3, and fermented at 25°C and 120 rpm for 15 days. Fermentation supernatants were collected at four time points: day 0 (C0/control), d...

2026-04-22 | MTBLS14352 | MetaboLights
TranscriptomicsThe nucleoid-associated protein HU controls three regulons that coordinate virulence and general physiology in Salmonella enterica serovar Typhimurium
The regulon of genes controlled by the HU nucleoid-associated proteins was examined in Salmonella enterica serovar Typhimurium (S. Typhimurium). DNA microarrays were used to detect the effect on the bacterial transcriptome of knockout mutations in the hupA, the hupB and in both the hupA and hupB gen...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium 
2011-03-22 | E-GEOD-22860 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of ORC and MCM binding sites and identification of replication origins in S. pombe
DNA replication of eukaryotic chromosomes initiates at a number of discrete loci, called replication origins. Distribution and regulation of origins are important for complete duplication of the genome. Here, we determined locations of Orc1 and Mcm6, components of pre-replicative complex (pre-RC),...
ORGANISM(S): Schizosaccharomyces pombe 
2010-06-11 | E-GEOD-6523 | biostudies-arrayexpress
TranscriptomicsExpression changes in Tetrahymena thermophila TRX1 and EZL2 gene knockouts and after hydroxyurea (HU) treatment
12 genome-wide microarrays to investigate the Tetrahymena thermophila gene expression changes in TRX1 and EZL2 gene knockout and hydroxyurea (HU) treatment conditions. For the TRR1 knockout (KO) condition, wild type (WT427) cells and TRX1 KO cells were cultured using 1XSPP, 30 degrees, 100 rpm shaki...
ORGANISM(S): Tetrahymena thermophila 
2013-09-04 | E-GEOD-44990 | biostudies-arrayexpress
UnknownFormation of Natural Magnesium Silica Hydrate (M-S-H) and Magnesium Alumina Silica Hydrate (M-A-S-H) Cement.
Not available
S-EPMC10934351 | biostudies-literature
TranscriptomicsTranscription profiling of S. pombe reveals Cyclin dependent kinase inhibits re-initiation of a normal S-phase program during G2
To achieve faithful replication of the genome once in each cell cycle, re-initiation of S-phase is prevented in G2 and origins are restricted from re-firing within S-phase. We have investigated the block to re-replication during G2 in fission yeast. The DNA synthesis that occurs when G2/M cyclin d...
ORGANISM(S): Schizosaccharomyces pombe 
2009-05-13 | E-MTAB-105 | biostudies-arrayexpress
TranscriptomicsAltered genes expression profile of Rep2 mutants in Fission Yeast upon HU treatment.
Expression profiles indicate that C-terminal of rep2 is essential for its transactivation activity. Keywords: rep2 mutants cells treated with 8 mM HU for different time points vs wildtype untreated cells We analyzed 40 arrays for rep2 mutants cells treated with 8 mM HU to wild type cells.
ORGANISM(S): Schizosaccharomyces pombe 
2010-05-16 | E-GEOD-10901 | biostudies-arrayexpress
MetabolomicsRevealing the Adaptive Metabolic Differences of Different Sheep Breeds in Plateau Areas Based on the Gut-Heart Axis

Gut microbiota plays a significant role in maintaining the homeostasis of the gut internal environment, and the volatile fatty acids (VFAs) produced by it are the main source of energy utilization for the host. The heart, as a key metabolic organ of the body, its energy metabolism efficiency dire...

2025-09-11 | MTBLS12982 | MetaboLights
TranscriptomicsTransfer of 5d old Col-0 and WEE1 KO seedlings to medium supplemented with 2mM HU for 0h-5h-24h
Col-0 and WEE1KO (wee1-1 and wee1-2) were germinated on control medium on a nylon mesh and transferred 5 days after germination to medium supplemented with 2 mM HU. Samples were harvested at three different time points after transfer: 0 h, 5 h, and 24 h. All sampling points were performed in four in...
ORGANISM(S): Arabidopsis thaliana 
2011-07-24 | E-MEXP-3053 | biostudies-arrayexpress
TranscriptomicsComparative transcriptomics of the model entomopathogenic fungi Metarhizium anisopliae and M. acridum during infection on different insects
We used RNA-Seq to compare transcriptional responses of M. anisopliae and M. acridum to infection of the optically clear hind wings of adult locusts and cockroaches. It was calculated that >82% of predicted M. anisopliae genes and >88% of predicted M. acridum genes were expressed during pre-penetrat...
ORGANISM(S): Metarhizium acridum 
2011-01-31 | E-GEOD-24938 | biostudies-arrayexpress
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