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ProteomicsQuantitative proteomic analysis of four subtypes of M2 macrophages
In this study, we used mass spectrometry and label-free quantification (LFQ) to characterize the global proteomics of polarized (M1, M2a, M2b, M2c, and M2d) and unpolarized (M0) phenotypes of macrophages from human THP-1 monocytes. The results described the biological functions of the four M2 macrop...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD022320 | Pride
M2 macrophage Prm Polarization Biomarker Lc-ms/ms 
ProteomicsSite-specific N-glycoproteomic analysis of four M2 macrophage subtypes derived from human THP-1 cells
In this study, we performed site-specific N-glycoproteomic analysis of THP-1 derived four M2 macrophage subtypes (M2a, M2b, M2c, and M2d) by StrucGP method combined with 2D-LC-MS/MS analysis, and revealed the distribution regularities and characters of N-glycans.
ORGANISM(S): Homo sapiens (Human) 
2025-12-23 | PXD048964 | Pride
Glycoproteome M2 subtypes Macrophage 
TranscriptomicsExpression data from polarized macrophages: effect of p53
p53 is critically important in preventing oncogenesis but its role in non-cancer biology remains unclear. Macrophages exist as two subtypes (M1 and M2). Nutlin-3a (p53 activator) inhibits M2 gene expression and phenotype. p53 acts by suppressing transcription of c-Myc and thence regulates expressio...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-53321 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of acute myeloid leukemia samples from Polish adult AML-M1 and M2 patients
Acute myeloid leukemia (AML) is the most common and severe acute leukemia diagnosed in adults. Although it is one of the most studied cancers, this is the first study of Polish population of AML patients. The data were collected with the use of home-made boutique array. The additional advantage is p...
ORGANISM(S): Homo sapiens 
2017-12-31 | E-MTAB-5434 | biostudies-arrayexpress
ProteomicsMyeloid cell-expressed MNDA enhances M2 polarization to facilitate the metastasis of hepatocellular carcinoma
Proteomic data of exosomes induced into M2 macrophage-derived cells after THP-1 knockdown of MNDA
ORGANISM(S): Homo Sapiens 
2024-03-20 | PXD050839 |
UnknownPrimary Human M2 Macrophage Subtypes Are Distinguishable by Aqueous Metabolite Profiles.
Not available
S-EPMC10889249 | biostudies-literature
UnknownOpposite Effects of M1 and M2 Macrophage Subtypes on Lung Cancer Progression.
Not available
S-EPMC4585843 | biostudies-literature
TranscriptomicsTwo faces of polarized macrophages: differential effects of M1 and M2 macrophage subtypes on lung cancer progression
Macrophages in tumor microenvironment have been characterized as M1- and M2-polarized subtypes. This study sought to investigate the effects of different macrophage subtypes on the biological behavior and global gene expression profiles of lung cancer cells. Expression microarray and bioinformatics ...
ORGANISM(S): Homo sapiens 
2016-08-25 | GSE50658 | GEO
UnknownProteomic characterization of four subtypes of M2 macrophages derived from human THP-1 cells.
Not available
S-EPMC9110321 | biostudies-literature
TranscriptomicsGene-expression molecular subtyping of triple-negative breast cancer tumours: importance of immune response
Triple-negative (TN) breast cancers need to be refined in order to identify therapeutic subgroups of patients. We conducted an unsupervised analysis of microarray gene-expression profiles of 107 TN breast cancer patients and undertook robust functional annotation of the molecular entities found by ...
ORGANISM(S): Homo sapiens 
2015-05-19 | E-GEOD-58812 | biostudies-arrayexpress
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