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Human neurodevelopment requires differentiating neurons to establish large networks of connections in a highly stereotyped manner. Neuronal differentiation in particular, requires RNA-binding proteins to spatiotemporally regulate thousands of different mRNAs. Yet, how these proteins precisely relate...
ORGANISM(S): Homo sapiens (Human) 
2024-06-10 | PXD034341 | Pride
Recognition of m6A RNA by the non-canonical reader IMP1
m6A methylation is the prevalent post-transcriptional modification in eukaryotic mRNAs and provides an essential layer of regulation in organismal development and in disease. The information encoded by m6A methylation is integrated into existing RNA regulatory networks by the binding of an expanding...
ORGANISM(S): Homo sapiens 
2024-11-01 | GSE214367 | GEO
m6a methylation drives IMP1 regulation during human neuronal differentiation.
m6a methylation drives IMP1 regulation during human neuronal differentiation [iCLiP]
m6a methylation drives IMP1 regulation during human neuronal differentiation [miCLIP]
m6a methylation drives IMP1 regulation during human neuronal differentiation [RNA-seq]
This SuperSeries is composed of the SubSeries listed below.
ORGANISM(S): Homo sapiens 
2024-04-13 | GSE203571 | GEO
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