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ProteomicsMass spectrometry–based proteomic profiling of pleural tissue
This dataset contains mass spectrometry-based proteomic data generated from pleural tissuesamples.Proteins were extracted, digested, and labeled using TMT isobaric labeling for quantitative analysis. Samples were analyzed using LC–MS/MS to profile the global proteome.The dataset includes raw mass sp...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD073793 | Pride
Mass spectrometry  lc–ms/ms  pleural tissue 
ProteomicsA lipid–immune network signature defines susceptibility to asparaginase-associated pancreatitis
Asparaginase is essential for curing acute lymphoblastic leukemia (ALL), but its use is limited by asparaginase-associated pancreatitis (AAP), a severe and unpredictable toxicity lacking validated prospective biomarkers. To define early systemic features of susceptibility, we performed longitudinal ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-31 | PAD000033 | Pride
Asparaginase associated pancreatitis Olink 
UnknownRisk and protection of different rare protein-coding variants of complement component C4A in age-related macular degeneration.
Not available
S-EPMC10859408 | biostudies-literature
MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
UnknownPreliminary Results on the Long-Term Effects of Dextromethorphan on MDMA-Mediated Serotonergic Deficiency and Volumetric Changes in Primates Based on 4-[18F]-ADAM PET/MRI.
Not available
S-EPMC9175743 | biostudies-literature
ProteomicsNuclear Paxillin Modulates Alternative Splicing Programs in Neurons during Sensitive Periods of Brain Development
During sensitive postnatal periods, brain neural circuits undergo significant refinement coincident with widespread neuronal alternative splicing events in which hundreds of genes alter their splice site selection to generate isoforms essential for synaptic plasticity. Here, we reveal that neuronal ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-08 | PXD060131 | Pride
Neuron Brain Rat Cortex Paxillin Alternative splicing 
MetabolomicsCustomized Consensus Spectral Library Building for Untargeted Quantitative Metabolomics Analysis with Data Independent Acquisition Mass Spectrometry and MetaboDIA Workflow
Data independent acquisition-mass spectrometry (DIA-MS) coupled with liquid chromatography is a promising approach for rapid, automatic sampling of MS/MS data in untargeted metabolomics. However, wide isolation windows in DIA-MS generate MS/MS spectra containing a mixed population of fragment ions t...
2018-03-26 | MTBLS417 | MetaboLights
UnknownA deep-learning retinal aging biomarker for cognitive decline and incident dementia.
Not available
S-EPMC11881618 | biostudies-literature
UnknownOmega-3 Polyunsaturated Fatty Acids as a Protective Factor for Myopia.
Not available
S-EPMC11606739 | biostudies-literature
UnknownA comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation.
Not available
S-EPMC8602937 | biostudies-literature
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