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During sensitive postnatal periods, brain neural circuits undergo significant refinement coincident with widespread neuronal alternative splicing events in which hundreds of genes alter their splice site selection to generate isoforms essential for synaptic plasticity. Here, we reveal that neuronal ...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-08-08 | PXD060131 | Pride
The objective was to perform protein identification by ESI-LC-MSMS on a sample subjected to Acyl-RAC assay in order to study protein palmitoylation. The user transfected human paxillin (mCherry-paxillin-CAIL) into a mouse cell line and performed Acyl-RAC assay. The aim of this analysis was to determ...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-30 | PXD023810 | Pride
Paxillin regulates genomic networks in prostate cancer [PC3]
Paxillin regulates genomic networks in prostate cancer [LNCaP]
Paxillin regulates genomic networks in prostate cancer [C4-2]
We have established that human cytomegalovirus (HCMV) infection modulates the biology of target primary blood monocytes, allowing HCMV to use monocytes as 'vehicles' for its systemic spread. HCMV infection of monocytes results in rapid induction of PI(3)K and NF-kB activity. Integrins, which are u...
ORGANISM(S): Homo sapiens 
Nuclear Paxillin Modulates Alternative Splicing Programs in Neurons during Sensitive Periods of Brain Development
During sensitive postnatal periods, brain neural circuits undergo significant refinement coincident with widespread neuronal alternative splicing events in which hundreds of genes alter their splice site selection to generate isoforms essential for synaptic plasticity. Here, we reveal that neuronal ...
ORGANISM(S): Mus musculus 
2025-08-07 | GSE288599 | GEO
We report that the adaptor protein, paxillin, regulates some androgen responsive genes in the castration sensitive prostate cancer cell line, LNCaP.
ORGANISM(S): Homo sapiens 
2019-08-01 | GSE131726 | GEO
We report that the adaptor protein, paxillin, regulates some proliferative and apoptotic genes in the castration resistant prostate cancer cell line, PC3.
ORGANISM(S): Homo sapiens 
2019-08-01 | GSE131730 | GEO
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