Sort   by:  
 Page size 
ProteomicsSpiroplasma eriocheiris restricts Eriocheir sinensis Wnt signaling pathway to promote pothogen infection and cause host tremor
Spiroplasma eriocheiris, has been identified as a novel lethal pathogen of Eriocheir sinensis tremor disease (TD), one neurological disease with typically paroxysmal tremors of the pereiopod. This pathogen infected and multiplied in the hemocytes of E. sinensis as the first target cells, and then fo...
ORGANISM(S): Eriocheir sinensis (Chinese mitten crab) 
2025-10-06 | PXD022892 | Pride
Wnt signaling pathway  eriocheir sinensis  spiroplasma eriocheiris  tremor disease  thoracic ganglion 
ProteomicsProtein phosphorylation and N-glycosylation in the early stage of Spiroplasma eriocheiris infect Eriocheir sinensis
As a novel lethal pathogen of Eriocheirsinensistremor disease,Spiroplasma eriocheiris, has led into catastrophic economic losses in aquaculture.The hemocytes of E. sinensis is the first target cells of S. eriocheiris. Our study is the first time designed to understanding of the phosphoproteome and N...
ORGANISM(S): Eriocheir sinensis (Chinese mitten crab) 
2026-04-27 | PXD014116 | Pride
Phosphoproteome Eriocheir sinensis N-glycoproteome Spiroplasma eriocheiris Hemocytes 
ProteomicsHuman cholangiocarcinoma LC-MS/MS
The glycosylation landscape of Human cholangiocarcinoma (CCA), and how it affects CCA diagnosis and prognosis, has recently emerged as an appealing research field.In this study, we used chemical glycoproteomic analysis Click-iG for systematic profiling of intact glycopeptides in CCA and HIBEpiC cell...
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD048188 | Pride
Glycoproteomics Click-ig Cholangiocarcinoma 
TranscriptomicsGene expression profiles of hepatocyte-like cells derived from induced pluripotent stem cells (iPSCs) from donors with the Zellweger spectrum of peroxisome biogenesis disorders (PBD-ZSD) and healthy controls
Skin fibroblasts from individuals with PBD-ZSD, a rare autosomal recessive disorder caused by peroxisome assembly defects, show defects in lipid metabolism that provide the basis for clinical diagnostic tests, but are not among the cell types most affected by disease. To explore phenotypes of more c...
ORGANISM(S): Homo sapiens 
2015-05-21 | E-GEOD-69066 | biostudies-arrayexpress
MetabolomicsBifidobacterium animalis subsp. lactis BD1 restores neurotransmitter homeostasis in chronically stressed mice via tryptophan metabolic reprogramming

Background: Chronic psychological stress is a major precipitating factor for neuropsychiatric disorders, yet the underlying mechanisms remain incompletely understood. The gut-brain axis has emerged as a critical regulator of mood and behavior, but how specific commensal microbes modulate host neu...

2025-10-23 | MTBLS13208 | MetaboLights
ProteomicsProteome-Wide Characterization of Phosphorylation-Induced Conformational and Stability Changes in Breast Cancer
Large-scale studies of protein phosphorylation have generally focused on determining the sites and stoichiometry of phosphorylated proteins derived from different biological specimens such as cell lines and tissue samples. While such information is important for understanding the role of phosphoryla...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD007916 | Pride
Protein stability Phosphorylation Human breast cancer Protein conformation 
ProteomicsLarge-Scale Characterization of Phosphorylation-Induced Conformational and Stability Changes in Breast Cancer
Large-scale studies of protein phosphorylation have generally focused on determining the sites and stoichiometry of phosphorylated proteins derived from different biological specimens such as cell lines and tissue samples. While such information is important for understanding the role of phosphoryla...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD007878 | Pride
Protein stability Phosphorylation Human breast cancer Protein conformation 
ProteomicsProtein phosphorylation networks in Baylisascaris procyonis revealed by phosphoproteomic analysis
Background: Baylisascaris procyonis is an intestinal ascarid worm that parasitizes in raccoons and causes fatal neural, visceral, and ocular larva migrans in humans. Phosphorylated proteins and protein kinases have been studied as vaccine and drug target candidates against parasitic infections. Howe...
ORGANISM(S): Baylisascaris procyonis 
2025-08-04 | PXD066529 | Pride
Raccoon Liquid chromatography-mass spectrometry Signaling pathway Baylisascaris procyonis Phosphoproteome Function 
ProteomicsA cell-free platform for characterizing and producing therapeutic bacteriophages against biohazardous and antibiotic-resistant bacteria
Bacteriophages are potent therapeutics against biohazardous bacteria that are rapidly acquiring multidrug resistance. However, routine administration of bacteriophage therapy is currently impeded by a lack of safe phage production methodologies and insufficient phage characterization. We thus develo...
ORGANISM(S): Eggerthella phage P3 Enterobacteria phage T7 Escherichia coli Bacteria 
2022-07-20 | PXD019543 | Pride
E. coli Bacteriophage 
ProteomicsHuman tau 0N4R isoform hyperphosphorylation LC-MS/MS
Soluble aggregates of the microtubule-associated protein tau have been challenging to assemble and characterize, despite their important role in the development of tauopathies. We found that sequential hyperphosphorylation by protein kinase A in conjugation with either glycogen synthase kinase 3beta...
ORGANISM(S): Homo sapiens (Human) 
2022-04-13 | PXD033127 | Pride
Hyperphosphorylation Tau Human Lc-ms/ms 
Sort   by:  
 Page size