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MetabolomicsAbsence of tmRNA Increases the Persistence to Cefotaxime and the Intercellular Accumulation of Metabolite GlcNAc in Aeromonas veronii
Bacterial persisters are a small proportion of phenotypically heterogeneous variants with the transient capability to survive in high concentrations of antibiotics, causing recurrent infections in both human and aquatic animals. Transfer-messenger RNA (tmRNA), which was encoded by the ssrA ge...
2021-10-18 | MTBLS1182 | MetaboLights
ProteomicsMULTI-TARGETED FLAVONOID INHIBITION OF THE PATHOGENIC BACTERIUM STAPHYLOCOCCUS AUREUS: A Proteomic Characterization
Growth inhibition of the pathogen Staphylococcus aureus with currently available antibiotics is problematic in part due to bacterial biofilm protection. While Although the recently characterized natural products, including 3´,4´,5-trihydroxy-6,7-dimethoxy-flavone [1], 3´,4´,5,6,7-pentahydroxy-flavon...
ORGANISM(S): Staphylococcus aureus 
2017-05-30 | PXD006030 | Pride
Antibacterial flavonoids  lc-ms/ms proteomics  multi-targeted bacterial inhibition Staphylococcus aureus 
ProteomicsEnhanced Quantitative LC-MS/MS Analysis of N-linked Glycans Derived from Glycoproteins Using Sodium Deoxycholate Detergent
Protein glycosylation is a common protein post-translational modification (PTM) in living organisms and has been shown to associate with multiple diseases, and thus may potentially be a biomarker of such diseases. Efficient protein/glycoprotein extraction is a key step in the preparation of N-glycan...
ORGANISM(S): Homo sapiens (Human) 
2018-05-16 | PXD008687 | Pride
Acidic labile detergent Detergent removal Lc-ms/ms sample preparation N-glycomics Sodium deoxycholate 
ProteomicsProteomics-AQ-WLL-LSHLFQ-SD-data
Phosphoproteomics of Different Strains in Northern Japonica Rice
ORGANISM(S): Oryza Sativa 
2025-12-13 | PXD071994 |
ProteomicsIntegrated Transcriptomics, Proteomics and Glycomics for a Deeper Insight of the Mechanism of Breast Cancer Brain Metastasis: Emphasizing on Glycosylation
Breast cancer brain metastasis has been recognized as one of the central issues in breast cancer research. Elucidation of the process and pathway that mediate this step is expected to provide important clues for a better understanding of breast cancer metastasis. Increasing evidence suggests that th...
ORGANISM(S): Homo sapiens (Human) 
2020-05-26 | PXD010506 | Pride
Integrative omics analysis Glycomics Transcriptomics Proteomics Breast cancer brain metastasis 
ProteomicsComparative Membrane Proteomics Analyses of Breast Cancer Cell Lines to Understand the Molecular Mechanism of Breast Cancer Brain Metastasis
Breast cancer is the leading type of cancer in women. Breast cancer brain metastasis is considered as an essential issue in breast cancer patients. Membrane proteins play important roles in breast cancer brain metastasis that contributes to the cell adhesion and penetration of blood-brain barrier. T...
ORGANISM(S): Homo sapiens (Human) 
2017-05-23 | PXD005719 | Pride
Proteomics Breast cancer brain metastasis Membrane enrichment Differential expression analysis Lc-ms/ms 
ProteomicsProteomic raw data for ctrl HRECs, CAPSL knockdown HRECs, and CAPSL overexpression HRECs
The purpose of this project is to explore the changes in signaling pathways after CAPSL knockdown and overexpression, and to identify potential downstream target genes of CAPSL along with the signaling pathways they are involved in. Ultimately elucidating the molecular mechanisms underlying CAPSL pa...
ORGANISM(S): Homo sapiens (Human) 
2024-09-04 | PXD051696 | Pride
Hrecs  capsl  knockdown  overexpression 
TranscriptomicsmiR-27b synergizes with anticancer drugs
Drug resistance, caused by complex and redundant mechanisms, is a major obstacle in cancer treatment, especially in liver and kidney cancers. Combinational therapy of miRNAs, which concurrently target multiple pathways, with anticancer drugs represent a new strategy to improve the drug response. By ...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-53872 | biostudies-arrayexpress
ProteomicsIdentification of a 144-amino-acid Scaffold Protein for Extracellular Vesicle Engineering
Extracellular vesicles (EVs) have emerged as promising drug-delivery vehicles. Genetic engineering of a membrane-bound, EV-sorting scaffold protein empowers these cell-borne nanosized vesicles by installing targeting moieties on the surface and enriching therapeutic cargo in the lumen. However, the ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-27 | PXD057965 | Pride
Expi293f-evs Lc-s/ms 
ProteomicsThe analysis of RhMYB73-interacted proteins in rose by LC-MS
The size of plant lateral organs is determined by well-coordinated cell proliferation and cell expansion. Here, we report that miR159, an evolutionarily conserved microRNA, plays an essential role in regulating cell division in rose (Rosa hybrida) petals by modulating cytokinin catabolism. We uncove...
ORGANISM(S): Rosa Hybrid Cultivar 
PXD046197 |
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