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TranscriptomicsTranscription profiling of mouse oocytes to investigate age-associated increase in aneuploidy and changes in gene expression.
An increase in the incidence of aneuploidy is well documented with increasing maternal age, in particular in human females. Remarkably, little is known regarding the underlying molecular basis for the age-associated increase in aneuploidy, which is a major source of decreased fertility in humans. Us...
ORGANISM(S): Mus musculus 
2008-06-18 | E-GEOD-11667 | biostudies-arrayexpress
ProteomicsDeoxyhypusine synthase, an essential enzyme for hypusine biosynthesis, is required for proper exocrine pancreas development
Pancreatic diseases including diabetes and exocrine insufficiency would benefit from therapies that reverse cellular loss and/or restore cellular mass. The identification of molecular pathways that influence cellular growth is therefore critical for future therapeutic generation. Deoxyhypusine synth...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-10-30 | MSV000099697 | MassIVE
ProteomicsChlorogeni cacid compounds from sweetpotato (lpomoeabatatas L.) leaves facilitate megakaryocyte differentiationand thrombocytopoiesis via Pl3K/AkT pathway
Idiopathic thrombocytopenic purpura (lTP) is anautoimmune disorder characterized by antiplateletautoantibodies, thrombocytopenia, and bleeding. In thisstudy, a kind of active component, chlorogenic acidcompounds(CGAs)from sweetpotato leaves was isolatedby ionic liquids-ultrasound, which contains 6 i...
ORGANISM(S): Mus Musculus 
2024-08-15 | PXD054945 |
ProteomicsA global multi-regional proteomic map of the human cerebral cortex
In this study, four groups of the iTRAQ quantification experiment using 2D-LC-MS/MS analysis, one group of the label-free quantification experiment using 2D-LC-MS/MS analysis, one group of the PRM quantification experiment of the human brain tissue were included. Therefore, six subprojects are incl...
ORGANISM(S): Homo Sapiens 
2021-03-09 | PXD024613 |
ProteomicsIdentifying glycolysis in mitochondria as a new perspective on the pathogenesis of retinitis pigmentosa
The interaction proteins were obtained by immunoprecipitation (IP) of VWA8 using retinal pigment epithelium cell lysate.
ORGANISM(S): Homo Sapiens 
2026-03-29 | PXD076332 |
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