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UnknownPreliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma.
Not available
S-EPMC4226806 | biostudies-literature
TranscriptomicsA dual genetic constraint underlies the conservation of early brains in vertebrates
As the body plan, the embryonic brain bauplan reflects the shared features of vertebrate brains. Yet, disagreements among sparse histogenetic frameworks have undermined the bauplan’s power to trace homologies. Here, we generate and integrate five vertebrate single-cell multi-omic atlases of early em...
ORGANISM(S): Mus musculus 
2026-03-15 | E-MTAB-16735 | biostudies-arrayexpress
UnknownThe genome of M. acetivorans reveals extensive metabolic and physiological diversity.
Not available
S-EPMC187521 | biostudies-literature
TranscriptomicsMouse-Monkey Time-series
Viral and bacterial infections of the lower respiratory tract are major causes of mortality and morbidity worldwide. Alveolar macrophages line the alveolar spaces and are the first cells of the immune system to respond to invading pathogens. In the study we examined the response of alveolar macropha...
ORGANISM(S): Macaca_fascicularis 
2011-08-02 | E-MTAB-427 | biostudies-arrayexpress
TranscriptomicsLRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function [RNA-Seq]
Two separate pools of three Flox or two Lrh1t-/- pancreas RNA preparations was subjected to the Illumina RNA-seq protocol. Examination of mRNA levels in induced Lrh1 pancreas knockout and wild-type mice.
ORGANISM(S): Mus musculus 
2011-11-30 | E-GEOD-34030 | biostudies-arrayexpress
UnknownGenetic architecture of the acute and persistent immune cell response after radiation exposure.
Not available
S-EPMC10667298 | biostudies-literature
TranscriptomicsRepeated gestational exposure of mice to chlorpyrifos oxon is associated with paraoxonase 1 (PON1)-modulated effects in maternal and fetal tissues
Chlorpyrifos oxon (CPO), the toxic metabolite of the organophosphorus (OP) insecticide chlorpyrifos, causes developmental neurotoxicity in humans and rodents. CPO is hydrolyzed by paraoxonase-1 (PON1), with protection determined by PON1 levels and the human Q192R polymorphism. To examine how the Q19...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-58103 | biostudies-arrayexpress
GenomicsOncogene-Mediated Alterations in Chromatin Conformation
Emerging evidence suggests that chromatin adopts a non-random three-dimensional (3D) topology and that the organization of genes into structural hubs and domains affects their transcriptional status. How chromatin conformation changes in diseases such as cancer is poorly understood. Moreover, how on...
ORGANISM(S): Homo sapiens 
2012-05-23 | E-GEOD-37752 | biostudies-arrayexpress
UnknownWhole genome sequencing increases the diagnostic rate in Charcot-Marie-Tooth disease.
Not available
S-EPMC11370804 | biostudies-literature
UnknownEvaluating genetic susceptibility to Staphylococcus aureus bacteremia in African Americans using admixture mapping.
Not available
S-EPMC5435963 | biostudies-literature
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