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TranscriptomicsGDNF-RET signaling as a target in aromatase inhibitor resistant breast cancers
Understanding the complex molecular mechanisms underlying resistance to endocrine therapy is a major challenge in the treatment of estrogen receptor-positive (ER+) breast cancers. We have previously demonstrated that glial cell line-derived neurotrophic factor (GDNF) signaling via the receptor tyros...
ORGANISM(S): Homo sapiens 
2013-01-17 | E-MEXP-3662 | biostudies-arrayexpress
TranscriptomicsAM_GeneExpressionAfterIonisingRadiation
Abstract Purpose: There is a recognised need to develop new methods of high throughput, rapid and minimally invasive individual dose assessment for radiation exposure. The aim of this work is to establish a panel of highly radiation responsive genes suitable for biological dosimetry and to explore i...
ORGANISM(S): Homo sapiens 
2011-10-20 | E-TABM-1083 | biostudies-arrayexpress
TranscriptomicsEMT and stem cell properties in basal breast cells
Transcriptomic comparison of Epithelial and mesenchymal subpopulations within normal basal breast cell lines
ORGANISM(S): Homo sapiens 
2011-12-19 | E-MTAB-804 | biostudies-arrayexpress
TranscriptomicsAgilent_HGG_custom_CGH
Custom oligonucleotide array CGH. We designed two fine-tiling oligonucleotide microarrays to cover the specific amplicons observed at chromosome 2p22.1 and 10q11.21 This was undertaken using the Agilent custom array design tool e-Array (Agilent, Santa Clara, CA, USA; https://earray.chem.agilent.com/...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-MTAB-2340 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of breast cancer cell lines and correlations with fibroblast growth factor receptor (FGFR) signalling and repression
Baseline gene expression profiling of breast cancer cell lines and correlations with FGFR signalling and repression
ORGANISM(S): Homo sapiens 
2011-12-01 | E-MTAB-879 | biostudies-arrayexpress
TranscriptomicsIllumina Infinium HumanMethylation450 BeadChip profiling of paediatric high grade gliomas from the HERBY clinical trial
We have used Illumina Infinium HumanMethylation450 BeadChip array profiling to profile paediatric high grade gliomas within the HERBY clinical trial. The HERBY trial was a phase-II open-label, randomised, multicentre trial evaluating bevacizumab in patients with newly-diagnosed non-brainstem HGG bet...
ORGANISM(S): Homo sapiens 
2018-05-11 | E-MTAB-5552 | biostudies-arrayexpress
TranscriptomicsProfiling of SF188 ATRX isogenic glioma cells
Methylation profiling of SF188 paediatric high grade glioma cell line isogenic clones carrying CRISR/Cas9 frameshift deletions in ATRX
ORGANISM(S): Homo sapiens 
2019-06-01 | E-MTAB-7800 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Analysis of Embryonic Mammary Cells
The mammary primordium represents the earliest evidence of commitment to the mammary lineage. The primordium forms via inductive tissue interactions between its constitutive tissues, the mesenchyme and epithelium. Here, we describe an analysis of the transcriptome of the mammary bud epithelium and i...
ORGANISM(S): Mus musculus 
2011-11-11 | E-TABM-1099 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of benign epithelial and prostate cancer cell lines derived from the same patient
Copy number alterations in a matched pair of benign epithelial and prostate cancer cell lines derived from the same patient were assessed using array-based comparative genomic hybridisation (aCGH). the cancer cell line showed a gain of chromosome 7, deletion of chromosome 8, gains and losses in chro...
ORGANISM(S): Homo sapiens 
2006-08-04 | E-MEXP-803 | biostudies-arrayexpress
TranscriptomicsIllumina Infinium HumanMethylation 450k Profiling of paediatric diffuse type high grade gliomas and patient derived xenografts
Methylation array based profiling of paediatric diffuse type high grade glioma primary tumours and patient derived orthotropic xenografts (PDX) in mice.
ORGANISM(S): Homo sapiens 
2026-03-31 | E-MTAB-16763 | biostudies-arrayexpress
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