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ProteomicsIn-depth serum proteomics of hospitalized COVID-19 patients and PCR-negative healthy controls with HiRIEF LC-MS/MS
We performed in-depth MS-based plasma-proteome profiling in 20 hospitalised patients with COVID-19 and 7 healthy controls (PCR- and sero-negative for SARS-CoV-2) by high-resolution isoelectric focusing (HiRIEF) coupled with liquid chromatography and mass-spectrometry (LC-MS/MS). The SARS‐CoV‐2 PCR‐c...
ORGANISM(S): Homo sapiens (Human) 
2023-09-01 | PXD037486 | Pride
Covid-19 Human Serum Plasma Sars-cov-2 Hirief Lc-ms/ms 
UnknownRVAgene: Generative modeling of gene expression time series data.
Not available
S-EPMC8504625 | biostudies-literature
MetabolomicsTemporal characterization of serum metabolite signatures in lung cancer patients undergoing treatment
Lung cancer causes more deaths in men and women than any other cancer related disease. Currently, few effective strategies exist to predict how patients will respond to treatment. We evaluated the serum metabolomic profiles of 25 lung cancer patients undergoing chemotherapy ± radiation to evaluate t...
2017-01-19 | MTBLS200 | MetaboLights
ProteomicsGenetic context modulates aging and degeneration in the murine retina
This is the proteomics component of a multi-omics analysis of the aging murine retina. Age is a critical risk factor for vision-threatening retinopathies. Susceptibility to age-related retinal neurodegeneration is genetically influenced, however, no studies have addressed molecular retinal aging sig...
ORGANISM(S): Mus musculus (Mouse) 
2025-01-23 | PXD057861 | Pride
Genetic diversity Proteomics Retinal vascular disease Tmt Wsb Retinitis pigmentosa Nzo Aging Retina Diabetic retinopathy Lc-ms/ms 
ProteomicsCx37 Phosphorylation and cell cycle regulation
Using alanine and aspartate substitutions to mimic dephosphorylated and phosphorylated Cx37, respectively, we showed that induced expression of Cx37 in rat insulinoma cells could arrest cell cycle progression, support cell cycle progression or cause cell death in a phosphosite specific manner. In th...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-13 | PXD012191 | Pride
Gap junction  growth arrest  proliferation  cell death  differential phosphorylation 
UnknownImplementation Of New Mexico's 'No Behavioral Health Cost Sharing' Law: A Qualitative Study.
Not available
S-EPMC11884875 | biostudies-literature
MetabolomicsNon-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions

From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
MetabolomicsHost Tree and Geography Induce Metabolic Shifts in the Epiphytic Liverwort Radula complanata
Bryophytes are prolific producers of unique, specialized metabolites that are not found in other plants. As many of these unique natural products are potentially interesting, for example, pharmacological use, variations in the production regarding ecological or environmental conditions have not ofte...
2026-01-29 | MTBLS6740 | MetaboLights
UnknownHuman muscle activity and lower limb biomechanics of overground walking at varying levels of simulated reduced gravity and gait speeds.
Not available
S-EPMC8279339 | biostudies-literature
MetabolomicsConnecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography
Our understanding of metabolic interactions between small symbiotic animals and bacteria or parasitic eukaryotes that reside within their bodies is extremely limited. This gap in knowledge originates from a methodological challenge, namely to connect histological changes in host tissues induced by b...
2021-07-06 | MTBLS2639 | MetaboLights
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