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TranscriptomicsDysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
The progressive loss of CNS myelin in patients with multiple sclerosis (MS) has been proposed to result from the combined effects of damage to oligodendrocytes and failure of remyelination. A common feature of demyelinated lesions is the presence of oligodendrocyte precursors (OLPs) blocked at a pre...
ORGANISM(S): Mus musculus 
2009-12-10 | E-GEOD-19403 | biostudies-arrayexpress
UnknownFANCM, BRCA1, and BLM cooperatively resolve the replication stress at the ALT telomeres.
Not available
S-EPMC5530707 | biostudies-literature
UnknownSequencing of the IL6 gene in a case-control study of cerebral palsy in children.
Not available
S-EPMC3881497 | biostudies-literature
UnknownIn depth comparison of an individual's DNA and its lymphoblastoid cell line using whole genome sequencing.
Not available
S-EPMC3473256 | biostudies-literature
UnknownWhole genome sequences of 2 octogenarians with sustained cognitive abilities.
Not available
S-EPMC4346472 | biostudies-literature
UnknownAstrocyte-encoded positional cues maintain sensorimotor circuit integrity.
Not available
S-EPMC4057936 | biostudies-literature
UnknownIn vivo phosphoproteome of human skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS.
Not available
S-EPMC2783959 | biostudies-literature
UnknownGenetic associations with brain cortical thickness in multiple sclerosis.
Not available
S-EPMC4857705 | biostudies-literature
TranscriptomicsLongitudinal expression profiling in whole blood of multiple sclerosis patients and controls
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41850 | biostudies-arrayexpress
Transcriptomicslongitudinal expression profiling in whole blood of multiple sclerosis patients and controls [MS vs Ctrl Discovery dataset]
Multiple sclerosis is the most common autoimmune disease of the central nervous system. Studying whole blood RNA from a cohort of 195 MS patients and 66 healthy controls, we identified gene expression signatures for interferon treatment and disease status by microarray analysis. Blood was collected ...
ORGANISM(S): Homo sapiens 
2013-06-17 | E-GEOD-41848 | biostudies-arrayexpress
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