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TranscriptomicsGene expression pattern of alveolar macrophages of allergic asthmatics in comparison with control subjects
The implication of alveolar macrophages (AM) in asthma, a Th2 disease, has not been well characterized. Thus, the goal of this study is to better characterize AM phenotype of allergic asthmatic compared with normal subjects using genomic expression analyses. Microarray analyses were performed with A...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-22528 | biostudies-arrayexpress
TranscriptomicsComparison of two sets of microarray experiments to define allergic asthma expression pattern
Allergic asthma is a complex trait. Several approaches have been used to identify biomarkers involved in this disease. This study aimed at demonstrating the relevance and validity of microarrays in the definition of allergic asthma expression pattern. The authors compared the transcript expressions ...
ORGANISM(S): Homo sapiens 
2012-10-18 | E-GEOD-41649 | biostudies-arrayexpress
GenomicsEGAD00000000047
Signal data for from 3 recurrent and 1 ovarian primary Granulosa Cell Tumour samples
EGAD00000000047 | EGA
GenomicsEGAD00000000048
Sequencing data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample
EGAD00000000048 | EGA
GenomicsEGAD00000000049
RNA-SEQ data from oestrogen-receptor-alpha-positive metastatic lobular breast cancer sample
EGAD00000000049 | EGA
GenomicsEGAD00000000046
RNA-SEQ data from 3 recurrent and 1 ovarian primary Granulosa Cell Tumour samples
EGAD00000000046 | EGA
GenomicsMutation of FOXL2 in granulosa cell tumors of the ovary
We generated paired-end RNA-Seq data using the Illumina Genome Analyzer II platform for four adult granulosa cell tumours (GCTs) of the ovary (1 primary, 3 recurrent). We screened this data for the presence of GCT specific sequence variants and detected a non-synonymous mutation in the FOXL2 gene th...
EGAS00000000040 | EGA
GenomicsMutational evolution in a lobular breast tumour profiled at single nucleotide resolution
We have used next generation sequencing to sequence genomes (>43-fold coverage) and transcriptomes of an oestrogen-receptor-alpha-positive metastatic lobular breast cancer at depth. We found 32 somatic non-synonymous coding mutations present in the metastasis, and measured the frequency of these som...
EGAS00000000054 | EGA
GenomicsEGAD00000000114
Whole transcriptome sequence data from 18 ovarian clear-cell carcinoma samples and one TOV21G ovarian clear-cell carcinoma cell line
EGAD00000000114 | EGA
GenomicsARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas
We have sequenced the whole transcriptomes of 18 ovarian clear-cell carcinomas and 1 ovarian clear-cell carcinoma cell line and found somatic mutations in ARID1A (the AT-rich interactive domain 1A [SWI-like] gene) in 6 of the samples. ARID1A encodes BAF250a, a key component of the SWI–SNF chromati...
EGAS00000000075 | EGA
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