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ProteomicsIntegrated Multiomics analysis to infer covid 19 biological insights
analysis of 57 sever covid patients's plasma samples for untargeted shotgun proteomics and metabolomics
ORGANISM(S): Homo sapiens (Human) 
2023-02-01 | PXD033335 | Pride
Proteomics Metabolomics Covid Multiomis 
ProteomicsFunctional Microbial Shifts and Host-Microbiome Crosstalk in Colorectal Cancer: Evidence from a Metaproteomic Approach
Colorectal cancer incidence is surging in many low- and middle-income countries, including Egypt, partly due to urbanization and lifestyle changes. Metaproteomics remains underutilized in such settings. This study applies a metaproteomic approach to fecal samples from Egyptian CRC patients to identi...
ORGANISM(S): Homo sapiens (Human) 
2026-01-27 | PXD067235 | Pride
Colorectal cancer  metaproteomic  microbiome  dpp-4  cysteine 
ProteomicsHuman Wharton’s jelly mesenchymal stem cells secretome inhibits human SARS-CoV-2 and avian IBV coronaviruses
Human SARS-CoV-2 and avian IBV are highly contagious and deadly coronaviruses causing devastating respiratory diseases in human and chicken, respectively. Lacking effective therapies exacerbates the disease associated with SARS-CoV-2 and IBV infections. Thus, novel therapeutic agents are in demand f...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD030966 | Pride
Human Proteomcis Mesenchymal stem cells Sars-cov-2 Lcmsms 
Proteomicsthermotolerance of camel cells
acute and chronic heat shock were applied to camel cells
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2020-01-13 | PXD012159 | Pride
Proteomics Heatshock Camel 
ProteomicsHeat shock of camel oocytes
acute and chronic heatshock effect on camel oocytes
ORGANISM(S): Camelus dromedarius (Dromedary) (Arabian camel) 
2022-03-01 | PXD012199 | Pride
Heatshock Camel Oocyte 
ProteomicsMulti-Omics signature of Autism Spectral Disorder reveals microbial macromolecules
Changes in gut microbiota have been implicated in pathophysiology and cognitive capabilities of patients suffering from autism spectrum disorder. Yet, factors that mediate this interaction remain not fully understood. In this study, we analyzed stool samples from sever autistic pediatric patients an...
ORGANISM(S): Homo sapiens (Human) 
2025-01-29 | PXD026274 | Pride
Autism Meta-proteomics Disorders Meta-genomics Multiomics 
ProteomicsMulti-omics characterization of childhood rhabdomyosarcoma
Rhabdomyosarcoma (RMS) presents a significant challenge in the field of oncology as a high-grade, aggressive soft tissue sarcoma that originates from skeletal (striated) muscle cells which do not fully differentiate. This condition is characterized by two major molecular and histopathological subtyp...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD052488 | Pride
Multiomics Proteomics Metabolomics 
ProteomicsDiabetic microenvironment deteriorates the regenerative capacities of adipose mesenchymal stromal cells
Human adipose mesenchymal stromal cells cutltured in culture media containing diabetic patient serum or normal indvidual serum as control for 6 days and 1 month period
ORGANISM(S): Homo sapiens (Human) 
2024-06-22 | PXD036116 | Pride
Diabetic Adipose Mesenchymal stromal cells 
ProteomicsInteraction between Malat1 and miR-499-5p regulates Meis1 expression and function with a net impact on cell proliferation
Meis1 is a transcription factor involved in a broad range of functions including development and proliferation and has been previously shown to harness cell cycle progression. This study aimed to investigate the regulation of Meis1 by long non-coding RNAs (lncRNAs) and their sponged microRNAs (miRNA...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD054558 | Pride
Malat1 Meis1 Mir-499-5p Cell proliferation Gene regulation Non-coding rnas Cell cycle 
ProteomicsCrosstalk between type 2 diabetic microenvironment and human adipose tissue- derived pericytes
Pericytes (PCs) are multipotent contractile cells that wrap around the endothelial cells to maintain the blood vessel's functionality and integrity. The hyperglycemia associated with Type 2 diabetes mellitus (T2DM) was shown to impair the function of PCs and increase the risk of diabetes complicatio...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD048187 | Pride
Adipose tissue  pericytes Proteomics 
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