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MetabolomicsChronic exposure to tire rubber-derived contaminant 6PPD-quinone impairs sperm quality and induces the damage of reproductive capacity in male mice

The study investigates the effects of 6PPDQ on male fertility in adult mice. The findings of this study are essential as the effects of low-dose environmental factors of 6PPDQ on adult male infertility are unclear, with the increasing in male infertility. The results suggest that 6PPDQ adversely ...

2025-07-14 | MTBLS9432 | MetaboLights
MetabolomicsIdentification and Molecular analysis of the Y-specific CpMp gene controlling long male peduncles in papaya

Papaya is a fruit crop possessing XY sex chromosomes. The development of long 

male peduncles (Mp) is pivotal for the evolutionary transition from gynodioecy to 

dioecy. The gene, CpMp, which controls peduncle length, is one of the four genes 

contributing to...

2025-10-20 | MTBLS13183 | MetaboLights
ProteomicsProteomic analysis of the Plasmodium male gamete reveals a key role for glycolysis in flagellar motility
Gametogenesis and fertilization play crucial roles in malaria transmission. While male gametes are thought to be amongst the simplest eukaryotic cells and are proven targets of transmission blocking immunity, little is known about their molecular organization. For example, the pathways of energy met...
ORGANISM(S): Plasmodium sp. pBT9 
2014-08-18 | PXD001163 | Pride
Plasmodium Proteomics Gametogenesis Male gametes 
OtherForty-Four Novel Protein-Coding Loci Discovered Using a Proteomics Informed by Transcriptomics (PIT) Approach in Rat Male Germ Cells.
Data from ProteomeXchange, PXD ID: PXD000872. File: SPC_exc02_compil.msf.mgf. Published as part of Biol Reprod. 2014 Sep 10 . From the Abstract: {{i}} Spermatogenesis is a complex process, dependent upon the successive activation and/or repression of thousands of gene products, and ends with the pr...
ORGANISM(S): Mus_musculus_viruses,rattus_norvegicus_papillomavirus_1_ees_2009_uid40233,rat_coronavirus_parker_uid39313, Rat 
GPM32320003462 | GPMDB
Resource Reanalysis 
ProteomicsThe Cryptosporidium signaling kinase CDPK5 plays an important role in male gametogenesis and parasite virulence
The protozoan parasite Cryptosporidium is a leading cause of diarrhea associated mortality in young children. The parasite’s lifecycle involves a highly coordinated and timely progression from asexual proliferative to sexual stages leading to formation of the transmissible oocyst. Underlying molecul...
ORGANISM(S): Cellular Organisms 
2024-06-04 | PXD051082 | JPOST Repository
TranscriptomicsTranscriptomes of isolated rice gametes characterized by deep sequencing: Evidence for distinct sex-dependent chromatin and epigenetic states before fertilization
The formation of a zygote by the fusion of egg and sperm involves the two gametic transcriptomes. In flowering plants, the embryo sac embedded within the ovule contains the egg cell, while the pollen grain contains two sperm cells inside a supporting vegetative cell. The difficulties of collecting ...
ORGANISM(S): Oryza sativa Japonica Group 
2013-10-31 | E-GEOD-50777 | biostudies-arrayexpress
GenomicsActive DNA demethylation in plant companion cells reinforces transposon methylation in gametes
The Arabidopsis thaliana central cell, the companion cell of the egg, undergoes DNA demethylation prior to fertilization, but the targeting preferences and biological significance of this process remain unclear. Here, we show that active DNA demethylation mediated by the DEMETER DNA glycosylase acco...
ORGANISM(S): Arabidopsis thaliana 
2012-09-21 | E-GEOD-38935 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse polysome vs RNP fractions from testis obtained from prepuberttal and adult animals to investigate post transcriptional control mechanisms in gametes
Gametes rely heavily on post-transcriptional control mechanisms to regulate their differentiation. In eggs, the storage and selective temporal activation of maternal mRNAs is essential for normal development. In the male, transcription ceases during spermiogenesis necessitating the post-transcriptio...
ORGANISM(S): Mus musculus 
2007-11-23 | E-GEOD-4711 | biostudies-arrayexpress
Proteomicsgender-related secretome of Plasmodium berghei sexual stages
In this study, we applied a proteomic approach to identify proteins differentially released/secreted by female and male gametocytes of the rodent Plasmodium berghei activated to form gametes. We compared secreted molecules of the wild type gametocytes with those of a transgenic line defective in mal...
ORGANISM(S): Plasmodium Berghei Anka (ncbitaxon:5823) 
2019-12-04 | MSV000084655 | MassIVE
GenomicsBromodomain-dependent stage-specific male genome programming by Brdt [ChIP-Seq]
Male germ cell differentiation is a highly regulated multistep process initiated by the commitment of progenitor cells into meiosis and characterized by major chromatin reorganizations in haploid spermatids. We report here that a single member of the double bromodomain BET factors, Brdt, is a master...
ORGANISM(S): Mus musculus 
2012-08-30 | E-GEOD-39908 | biostudies-arrayexpress
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