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MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
MetabolomicsSilage-derived flavonoids reprogram rumen microbiota to improve milk fat synthesis via rumen-mammary gland axis

Inoculation with homofermentative lactic acid bacteria (LAB) effectively enhances the silage quality of forages. Moreover, feeding such LAB-inoculated silage modulates rumen microbiota composition and metabolites, thereby improving ruminant production performance. Nevertheless, the specific mecha...

2026-01-11 | MTBLS13651 | MetaboLights
MetabolomicsSilage-derived flavonoids reprogram rumen microbiota to improve milk fat synthesis via rumen-mammary gland axis

Inoculation with homofermentative lactic acid bacteria (LAB) effectively enhances the silage quality of forages. Moreover, feeding such LAB-inoculated silage modulates rumen microbiota composition and metabolites, thereby improving ruminant production performance. Nevertheless, the specific mecha...

2026-01-10 | MTBLS13648 | MetaboLights
TranscriptomicsTranscriptomic Analysis of Embryonic Mammary Cells
The mammary primordium represents the earliest evidence of commitment to the mammary lineage. The primordium forms via inductive tissue interactions between its constitutive tissues, the mesenchyme and epithelium. Here, we describe an analysis of the transcriptome of the mammary bud epithelium and i...
ORGANISM(S): Mus musculus 
2011-11-11 | E-TABM-1099 | biostudies-arrayexpress
TranscriptomicsRNA-Seq data from the milk somatic cell transcriptome of Assaf sheep in response to experimental inoculation of an Escherichia coli Lipopolysaccharide
This study evaluated the evolution of the host defensive molecular mechanisms triggered by mastitis caused by external agents or events, since it is known that mammary gland infections constitute a significant challenge in dairy sheep, impacting productivity and welfare. Thus, the aim of this study ...
ORGANISM(S): Ovis aries 
2024-10-09 | E-MTAB-13994 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of mammary gland cell subpopulations isolated from the transgenic mouse model FVB 11.5-kb-GFP.
The transgenic FVB/N 11.5kb-GFP mouse line was generated using the 11.5 kb s-SHIP promoter. During puberty, GFP expression in the mammary gland is specifically restricted to cap cells, which exhibit stem cell-like properties. To investigate the molecular basis underlying the differences between thes...
ORGANISM(S): Mus musculus 
2025-08-15 | E-MTAB-15385 | biostudies-arrayexpress
UnknownPolarized Secretion of Extracellular Vesicles by Mammary Epithelia.
Not available
S-EPMC6103817 | biostudies-literature
GenomicsSingle cell RNA-seq reveals heterogeneity and hierarchy of mouse mammary epithelia
Single cell RNA-seq reveals heterogeneity and hierarchy of mouse mammary epithelia
PRJNA433548 | ENA
TranscriptomicsExpression data from mammary gland during pregnancy and lactation of CBA/CaH, QSi5 and Advanced Intercross Line (AIL; CBA/CaH X QSi5, the 14th generation)
Previously we have shown significant differences in lactation performance, mammary gland histology and expression profiles of mammary transcriptome during peak-lactation (lactation day 9; L9) between the ordinary CBA/CaH (CBA) and the superior QSi5 strains of mice. In the present study, we compared ...
ORGANISM(S): Mus musculus 
2013-01-22 | E-GEOD-32020 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression during ovine adult mammary gland development
The mammary gland undergoes extensive remodeling between the begin- ning of pregnancy and lactation; this involves cellular processes including cell proliferation, differentiation, and apoptosis, all of which are under the control of numerous regulators. To unravel the role played by miRNA, we descr...
ORGANISM(S): Mus musculus 
2013-01-04 | E-GEOD-32654 | biostudies-arrayexpress
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