Mancias Joseph D JD

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Proteomics (2)
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pride (2)

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Mass Spectrometry (2)
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Publication Date

2026 (1)
2022 (1)

Release Date

2016 (1)

Lab affiliation

Division of Radiation and Genome Stability, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA Department of Radiation Oncology, Brigham and Women’s Hospital, Boston, MA 02115 (1)
Harvard Institutes of Medicine 2nd floor, Room 221 4 Blackfan Circle Boston, MA 02115 (1)

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BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

Inter-organellar communication is critical for cellular metabolic homeostasis. One of the most abundant inter-organellar interactions are those at the endoplasmic reticulum and mitochondria contact sites (ERMCS). However, a detailed understanding of the mechanisms governing ERMCS regulation and thei...

ORGANISM(S): Homo sapiens (Human)

2026-06-08 | PXD056917 | Pride

NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

Oncogenic KRAS rewires pancreatic ductal adenocarcinoma (PDAC) metabolism to promote dependence on autophagy and iron metabolism. NCOA4-mediated ferritinophagy links autophagy and iron metabolism as NCOA4 selectively targets ferritin, the cellular iron storage complex, via autophagy to the lysosome ...

ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse)

2022-08-17 | PXD033356 | Pride

Ferritinophagy Ncoa4 Iron Pdac

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Not available

S-EPMC4835977 | biostudies-literature

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