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HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. HMF3A cells cease proliferating by 4 days at 39Â...
ORGANISM(S): Homo sapiens 
Oats (Avena sativa L.) are a healthy food, being high in dietary fibre (e.g. β-glucans), antioxidants, minerals, and vitamins. Understanding the effect of variety and crop management on nutritional quality is important. The response of four oat varieties to increased nitrogen levels was investigated...
2021-04-26 | MTBLS1801 | MetaboLights
Klf4 is the zinc finger transcription factor indispensable for terminal maturation of epithelial tissues and part of group of proteins for the generation of pluripotent embryonic stem cells from differentiated tissues. No definitive in-vivo-function of Klf4 in the hematopoietic system has been estab...
ORGANISM(S): Mus musculus 
To determine changes in gene expression in primary fibroblasts undergoing replicative senescence, a direct comparison between early passage proliferating cells and senescent cells was performed. Frozen stocks of the primary fibroblasts (HMF3) from which the lines HMF3A and HMF3Dwt were derived (O'Ha...
ORGANISM(S): Homo sapiens 
HMF3A cells, created from adult human mammary fibroblasts by immortalisation with a thermolabile SV40 large T antigen and the catalytic sub-unit of human telomerase, undergo co-ordinated induction of cellular senescence upon inactivation of T antigen. The pSUPER-retro vector system (Brummelkamp, 200...
ORGANISM(S): Homo sapiens 
D1 ductal cells from human pancreatic exocrine tissue cultured in 2 different conditions, one with a proinflammatory cytokine cocktail and the other as a vehicle control. Observe differences between cyto and control in all samples and then just in the non-obese and non-diabetic group.
ORGANISM(S): Homo sapiens (Human) 
2026-06-24 | PXD074059 | Pride
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