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ProteomicsIdentification of proteins bound to chromatin of male meiotic cells.
Identification of lactic dehydrogenase C (LDHC)(but not lactic dehydrogenase A -LDHA) presence amoung chromatin bound proteins of pachytene/diplotene/diakinesis (PDD) cells isolated from Stra8-CAG-tdTomato mice testis. LDHC (but not LDHA) was found to be bound to chromosomes and centromeres of PDD c...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-23 | PXD039014 | Pride
Germ cells Spermatogenesis Mice Lc-ms/ms 
ProteomicsWhole cell proteimics of leptotene+zygotene(LZ) and pachytene+diplotene+diakinesis (PDD) of first meiosis prophase of spermatogenesis in male mouse.
2-hydroxyglutarate (2HG) is recognized as an epigenetic regulator in cancer and some transient biological processes. Of all organs, the testis harbors the highest baseline physiological levels of 2HG, yet it’s putative functions in germ cell biology are unknown. Here we show that 2HG is generated in...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-23 | PXD039015 | Pride
Testis Meiosis Spermatogenesis Lc-ms/ms 
UnknownA single-arm phase 2 study of abemaciclib in adult patients with recurrent grade 3 oligodendroglioma.
Not available
S-EPMC11815343 | biostudies-literature
UnknownBrain Connectivity Predicts Placebo Response across Chronic Pain Clinical Trials.
Not available
S-EPMC5082893 | biostudies-literature
UnknownIslet Gene View-a tool to facilitate islet research.
Not available
S-EPMC9366203 | biostudies-literature
UnknownReplication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study.
Not available
S-EPMC8382625 | biostudies-literature
UnknownDistinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study.
Not available
S-EPMC8564413 | biostudies-literature
UnknownIdentification of biomarkers for glycaemic deterioration in type 2 diabetes.
Not available
S-EPMC10156700 | biostudies-literature
UnknownAssociation study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia.
Not available
S-EPMC3401899 | biostudies-literature
UnknownProcalcitonin-Guided Use of Antibiotics for Lower Respiratory Tract Infection.
Not available
S-EPMC6197800 | biostudies-literature
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