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ProteomicsTemporal proteomics characterization of COVID-19 patient sera
We enrolled 37 SARS-CoV-2 positive patients including 17 short course (SC) COVID-19 patients (twice viral RNA detection negative over 24 hrs) and 20 COVID-19 long course (LC) COVID-19 patients. We also included 35 SARS-CoV-2 negative patients as control group. We collected 224 inactive serum samples...
ORGANISM(S): Homo Sapiens 
2022-07-26 | PXD035471 |
ProteomicsSOCS5-RBMX stimulates SREBP1-mediated lipogenesis to promote metastasis in HCC
SOCS5 stimulate the promoter of SREBP1 to induce de novo lipogenesis to promote HCC metastasis
ORGANISM(S): Homo Sapiens 
2024-01-22 | PXD048740 |
ProteomicsComprehensive kinomic study via a chemical proteomic approach reveals dynamic kinome reprogramming in hepatocellular carcinoma tissues
To identify kinases of potential therapeutic interest in HCC, a quantitative kinomic study of tumour and adjacent non-tumour liver tissues was performed using a chemical proteomic approach.
ORGANISM(S): Homo Sapiens 
2021-01-26 | PXD023806 |
ProteomicsNovel molecular glue degraders against broad range of myeloma and lymphoma cancer cell lines
Targeted protein degradation of neosubstrates plays a crucial role in treating hematological cancers with IMiDs therapy. However, the inevitable drug resistance and hematological toxicities remain persistent challenges, limiting their clinical efficacy. Herein, we present the discovery of a lead deg...
ORGANISM(S): Homo Sapiens 
2024-06-22 | PXD053334 |
ProteomicsUrinary Proteomic Characteristics of Hyperuricemia and Their Possible Links with the Occurrence of Hyperlipidemia and Type 2 Diabetes Mellitus
We performed label-free liquid chromatography MS/MS spectrometry analysis of urine samples from 26 HUA patients and 25 healthy controls, attempting to establish the possible protein links between hyperuricemia and these diseases by profiling urine proteome.
ORGANISM(S): Homo Sapiens 
2019-12-24 | PXD016900 |
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