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TranscriptomicsTranscription profiling of human squamous cell carcinoma of the head and neck cells reveals tumor growth and prognosis of squamous cell carcinoma of the head and neck is linked to protein kinase C alpha
Protein Kinase C alpha (PKC) is a critical mediator of cell signaling and cancer growth. We show that PKC inhibitors decrease proliferation in squamous cell carcinoma of the head and neck (SCCHN) cells and abrogate growth of SCCHN tumors in mouse xenografts. Analysis of gene expression arrays reveal...
ORGANISM(S): Homo sapiens 
2009-03-28 | E-GEOD-10299 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human trabecular meshwork cultured cells, non-glaucomatous and POAG tissue
The goal of this study was to contrast genome-wide gene expression profiles of cultured human trabecular meshwork (HTM) cells, to that of control and primary open angle glaucoma (POAG) HTM tissues. Total RNA from cultured HTM cells and HTM tissue dissected from control and POAG anterior segments fix...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4316 | biostudies-arrayexpress
UnknownRefuting phylogenetic relationships.
Not available
S-EPMC1574289 | biostudies-literature
UnknownSubstitutions in the amino-terminal tail of neurospora histone H3 have varied effects on DNA methylation.
Not available
S-EPMC3248561 | biostudies-literature
TranscriptomicsTimes series of cells synchronized by double thymidine block
HaCat cell cycle experiment: During the somatic cell cycle, DNA and epigenetic modifications in DNA and histones are copied to daughter cells. DNA replication timing is tightly regulated and linked to GC content, chromatin structure, andgene transcription, but how maintenance of histone modification...
ORGANISM(S): Homo sapiens 
2011-12-31 | E-MTAB-454 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human head and neck squamous cell carcinoma samples reveals a feed-forward loop involving protein kinase Calpha and microRNAs regulates tumor cell cycle
Patient selection and specimen collection. Thirty-six freshly frozen tumor samples were prospectively collected from patients undergoing surgery or biopsy for HNSCC at the University of North Carolina (UNC) at Chapel Hill (21 patients) and Vanderbilt University (15 patients). All tissues were snap-f...
ORGANISM(S): Homo sapiens 
2009-03-28 | E-GEOD-10300 | biostudies-arrayexpress
UnknownSun Navigation Requires Compass Neurons in Drosophila.
Not available
S-EPMC7301569 | biostudies-literature
UnknownAtlas-builder software and the eNeuro atlas: resources for developmental biology and neuroscience.
Not available
S-EPMC4050700 | biostudies-literature
UnknownConserved interfaces mediate multiple protein-protein interactions in a prokaryotic metabolon
Not available
S-SCDT-10_1038-S44320-025-00139-9 | biostudies-other
UnknownEpigenome-wide association study of placental co-methylated regions in newborns for prenatal opioid exposure.
Not available
S-EPMC12422002 | biostudies-literature
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