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MetabolomicsInvestigation of the threonine metabolism of Echinococcus multilocularis: EmTDH as a potential drug target in alveolar echinococcosis
Alveolar echinococcosis is a severe zoonotic disease caused by the fox tapeworm E. multilocularis. New treatment options are urgently needed. Whole-organism-based screening allows the discovery of potential new anti-echinococcal compounds, but suffers from low- to medium-throughput. An alternative a...
2026-09-14 | MTBLS10738 | MetaboLights
MetabolomicsMetabolomic analysis of alfalfa (Medicago sativa L.) root-symbiotic rhizobia responses under alkali stress
Alkaline salts (e.g., NaHCO3 and Na2CO3) causes more severe morphological and physiological damage to plants than neutral salts (e.g., NaCl and Na2SO4) due to differences in pH. The mechanism by which plants respond to alkali stress is not fully understood, especially in plants having symbotic relat...
2018-07-27 | MTBLS481 | MetaboLights
MetabolomicsMetabolomics-Driven Discovery of an Introduced Species and Two Malaysian Piper betle L. Variants
The differences in pungency of 'sirih' imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected M...
2022-03-21 | MTBLS2585 | MetaboLights
UnknownDataset of concentrations of free terpenes at different phenological stages in Vitis vinifera L. Shiraz, Cabernet Sauvignon, Riesling, Chardonnay and Pinot Gris.
Not available
S-EPMC6820309 | biostudies-literature
MetabolomicsLipopolysaccharides from Ralstonia solanacearum induce a broad metabolomic response in Solanum lycopersicum

Ralstonia solanacearum, one of the most destructive crop pathogens worldwide, causes bacterial wilt disease in a wide range of host plants. The major component of the outer membrane of Gram-negative bacteria, lipopolysaccharides (LPS), has been shown to function as elicitors of plant defense lead...

2023-08-08 | MTBLS7324 | MetaboLights
ProteomicsmCherry contains a fluorescent protein isoform that interferes with its reporter function
Fluorescent proteins are essential reporters in cell biology and molecular biology. Here, we reveal that red-fluorescent proteins possess an alternative translation initiation site that produces a short functional protein isoform. The short isoform creates significant background fluorescence that bi...
ORGANISM(S): Escherichia coli 
2022-04-19 | PXD032954 | Pride
Lc-msms Mcherry 
TranscriptomicsThe effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis; insights for early bactericidal activity
Background: Pyrazinamide (PZA) plays an essential part in the shortened 6-month tuberculosis (TB) treatment course due to its activity against slow-growing, semi-dormant organisms. We tested the paradigm that PZA preferentially targets slow growing cells of Mycobacterium tuberculosis that remain aft...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2016-03-25 | E-MTAB-4093 | biostudies-arrayexpress
UnknownCystatin M/E Variant Causes Autosomal Dominant Keratosis Follicularis Spinulosa Decalvans by Dysregulating Cathepsins L and V.
Not available
S-EPMC8312243 | biostudies-literature
UnknownBrachyury engineers cardiac repair competent stem cells.
Not available
S-EPMC7900595 | biostudies-literature
MetabolomicsIntracellular and extracellular metabolites from three strains of Prochlorococcus
Prochlorococcus is an abundant, cosmopolitan, marine cyanobacterium with ecotypes that vary temporally and spatially across oligotrophic regions of the global ocean. This group of organisms can serve as a model system to understand the accumulation of organic compounds synthesized by primary produce...
2018-10-23 | MTBLS567 | MetaboLights
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