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TranscriptomicsSpo11-oligo mapping in S. cerevisiae Ctf19/CCAN kinetochore sub-complex mutant mcm21
During meiosis, crossover recombination is essential to link homologous chromosomes and drive faithful chromosome segregation. Crossover recombination is non-random across the genome, and centromere-proximal crossovers are associated with an increased risk of aneuploidy, including Trisomy 21 in huma...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-15 | E-GEOD-72683 | biostudies-arrayexpress
ProteomicsMolecular mechanism targeting condensin for chromosome condensation
Faithful chromosome segregation requires packaging of the genome on both global and local scales. Condensin plays a crucial role at pericentromeres to resist spindle forces and ensure the oriented attachment of kinetochores to microtubules at mitosis. Here we demonstrate that budding yeast condensin...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-12-10 | PXD056626 | Pride
Chromosome segregation Dia Shugoshin Ipms Pericentromeres Condensin 
ProteomicsRewiring of the phosphoproteome executes two meiotic divisions
The cell cycle is ordered by a controlled network of kinases and phosphatases. To generate gametes via meiosis, two distinct and sequential chromosome segregation events occur without an intervening S phase. How canonical cell cycle controls are modified for meiosis is not well understood. Here, usi...
ORGANISM(S): Saccharomyces cerevisiae Saccharomyces cerevisiae (Baker's yeast) 
2026-09-12 | PXD045368 | Pride
Spo13 Saccharomyces cerevisiae Kinases Phosphorylation Meiosis Cell cycle 
ProteomicsMolecular mechanism targeting condensin for chromosome condensation.
Faithful chromosome segregation requires packaging of the genome on both global and local scales. Condensin plays a crucial role at pericentromeres to resist spindle forces and ensure the oriented attachment of kinetochores to microtubules at mitosis. Here we demonstrate that budding yeast condensin...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-12-10 | PXD056649 | Pride
Condensin Chromosome segregation Slim Cross-linking mass spectrometry Shugoshin 
ProteomicsSpecialisation of meiotic kinetochores revealed through a synthetic spindle assembly checkpoint strategy.
Meiosis creates haploid gametes through two sequential M phases. While many studies have focused on meiosis I, the molecular events which drive and define meiosis II are largely unknown. Here, we report a novel cell synchronization strategy which allows for collection of yeast cells arrested at meta...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-03-04 | PXD067911 | Pride
ProteomicsA functional genomics screen identifies genes required for Schizosaccharomyces pombe meiosis
Meiosis is a specialized cell division that generates gametes, such as eggs and sperm. Errors in meiosis result in miscarriages and are the leading cause of birth defects, however the molecular origins of these defects remain unknown. Studies in model organisms are beginning to identify the genes an...
ORGANISM(S): Schizosaccharomyces pombe 
2018-01-04 | PXD008245 | Pride
Schizosaccharomyces pombe Chromosome segregation Sporulation Meiosis 
UnknownPrevalence of Bartonella henselae and Bartonella clarridgeiae in an urban Indonesian cat population.
Not available
S-EPMC95657 | biostudies-literature
UnknownThe omega-3 polyunsaturated fatty acid eicosapentaenoic acid inhibits mouse MC-26 colorectal cancer cell liver metastasis via inhibition of PGE2-dependent cell motility.
Not available
S-EPMC3419914 | biostudies-literature
UnknownReliability and interrelations of seven proxy measures of cochlear synaptopathy.
Not available
S-EPMC6423440 | biostudies-literature
UnknownInterspecies protein substitution to investigate the role of the lyssavirus glycoprotein.
Not available
S-EPMC3709617 | biostudies-literature
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