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ProteomicsGlomerular proteomic profiling of kidney biopsies with hypertensive nephropathy reveals a signature of disease progression
Background and Objective: Hypertensive nephropathy (HN) requires a kidney biopsy as gold-standard for its diagnosis but histological findings are not entirely specific and lack specific prognostic markers. We aimed at defining prognostic candidate markers based on glomerular protein signatures. Meth...
ORGANISM(S): Homo sapiens (Human) 
2023-05-23 | PXD026709 | Pride
Human Microdissection Hypertensive nephropathy Kidney Glomerulus Proteomics 
ProteomicsCross-omics analysis of archival human renal cell carcinoma biopsies to identify emerging treatment avenues
Renal cell cancer is among the most common forms of cancer in humans, with around 35,000 deaths attributed to kidney carcinoma in the European Union (EU) in 2012 alone. Clear cell renal cell carcinoma (ccRCC) represents the most common form of kidney cancer and the most lethal of all genitourinary c...
ORGANISM(S): Homo sapiens (Human) 
2019-04-25 | PXD011681 | Pride
Immunoproteasome Proteomics Kidney cancer Cd74 Cross-omics 
ProteomicsDistinct protein signature of hypertension-induced damage in the renal proteome of the two-kidney, one-clip ratmodel
Background: Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-02-28 | PXD012889 | Pride
Hypertension 2k1c Juxtamedullary cortex Kidney 
ProteomicsPost-transplant diabetes mellitus after kidney transplantation
Diabetes mellitus (DM) after transplantation remains a crucial clinical problem in kidney transplantation. To obtain insights into molecular mechanisms underlying the development of post-transplant diabetes mellitus (PTDM) and its early impact on glomerular structures, here we comparatively analyze...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD042188 | Pride
Human Ptdm. t2dm Kidney Tranplantation 
UnknownSARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.
Not available
S-EPMC7995808 | biostudies-literature
UnknownTiming of surgery following SARS-CoV-2 infection: an international prospective cohort study.
Not available
S-EPMC8206995 | biostudies-literature
UnknownSARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study.
Not available
S-EPMC8652887 | biostudies-literature
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