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Uncovering the molecular mechanism of stem cell self-renewal is critical to broaden current therapeutic applications and to understand how its de-regulation may lead to pathological conditions. In this work, we report changes in gene expression and related cell processes during conditions of high in...
ORGANISM(S): Homo sapiens 
Immunoprecipitation with anti-FLAG antibody in nuclear extracts of FLAG-BMAL1 expressing mESCs. LC MS/MS was used to analyze the interactome of BMAL1 in mESCs.
ORGANISM(S): Mus musculus (Mouse) 
2025-08-16 | PXD050769 | Pride
Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin's lymphoma, is clinically heterogeneous: 40% of patients respond well to current therapy and have prolonged survival, whereas the remainder succumb to the disease. We proposed that this variability in natural history refle...
ORGANISM(S): Homo sapiens 
Renal cell cancer is among the most common forms of cancer in humans, with around 35,000 deaths attributed to kidney carcinoma in the European Union (EU) in 2012 alone. Clear cell renal cell carcinoma (ccRCC) represents the most common form of kidney cancer and the most lethal of all genitourinary c...
ORGANISM(S): Homo sapiens (Human) 
2019-04-25 | PXD011681 | Pride
An untargeted metabolomics approach using UPLC-ESI-QTOF-MS was performed to explore the metabolome of iceberg lettuce and the changes related to storage time and genetics. Two cultivars with different browning susceptibility, fast- browning (FB) and slow-browning (SB) were studied juts after cutting...
2017-08-03 | MTBLS343 | MetaboLights
ATP-dependent chromatin remodeling enzymes re-position and evict nucleosomes at specific genomic loci and therefore are essential regulators of all DNA dependent processes. They act in the context of large multiprotein complexes. The malaria-causing parasite Plasmodium falciparum (Pf) possesses a re...
ORGANISM(S): Plasmodium falciparum 
2024-10-17 | PXD041155 | Pride

Blood metabolomics of 12-week-old female and male C57BL/6J mice that were exposed to either a control or an unhealthy high-fat/high-sugar (HFHS) diet during early-life, or early-life HFHS diet supplemented with a microbiota-targeted intervention (either a prebiotic combination (fructo-oligosaccha...

2026-01-27 | MTBLS12714 | MetaboLights
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