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ProteomicsNicotinamide Mononucleotide Requires SIRT3 to Improve Cardiac Function and Bioenergetics in a Friedreich’s Ataxia Cardiomyopathy Model
Martin et al. JCI Insigh (2017). Increasing NAD+ levels by supplementing with the precursor nicotinamide mononucleotide (NMN) improves cardiac function in multiple mouse models of disease. While NMN influences several aspects of mitochondrial metabolism, the molecular mechanisms by which increased N...
ORGANISM(S): Mus musculus (Mouse) 
2017-07-21 | PXD006754 | Pride
Nmn Friedreich’s ataxia Heart failure Sirt3 Acetylation 
ProteomicsAdaptation of Dinoroseobacter shibae to different kinds of oxidative stress
The Gram-negative photoheterotrophic bacterium Dinoroseobacter shibae is a member of the high abundant marine Roseobacter group. Living in the photic zone environment of marine ecosystems D. shibae is frequently exposed to oxygen. Oxic environments are hazardous and therefore effective defense mecha...
ORGANISM(S): Dinoroseobacter shibae (strain DFL 12) 
2021-03-12 | PXD013791 | Pride
Diamide Paraquat Dinoroseobacter shibae Oxidative stress Hydrogen peroxide Gelc-ms/ms Rhizobial iron regulator 
TranscriptomicsComparison of Flk-1+/PDGFRa+(Flk-1PRa+(DP)) population from Etv2Het vs Etv2KO ES cells
Screening for genes regulated by Etv2 within Flk-1+/PDGFRa+ ES derived mesoderm.Microarray analysis performed to screen for the candidate genes regulated by Etv2. TT2 ES cells differentiated on OP9 feeder cells were sorted using Flk-1 and PDGFRa antibodies.Gene expressions from these two population...
ORGANISM(S): Mus musculus 
2011-08-30 | E-GEOD-31744 | biostudies-arrayexpress
UnknownHLA-DP on Epithelial Cells Enables Tissue Damage by NKp44<sup>+</sup> Natural Killer Cells in Ulcerative Colitis.
Not available
S-EPMC10529779 | biostudies-literature
UnknownVitamin D status is independently associated with plasma glutathione and cysteine thiol/disulphide redox status in adults.
Not available
S-EPMC4115025 | biostudies-literature
UnknownRenal Resistive Index Is Associated With Inactive Matrix Gla (γ-Carboxyglutamate) Protein in an Adult Population-Based Study.
Not available
S-EPMC6818003 | biostudies-literature
ProteomicsContext-dependent regulatory mechanisms control site-specific information processing within the MEK/ERK module
The impact of the cellular context and receptor type on the dynamics of phosphorylation cycles in signaling pathways are unclear. We employ an unbiased approach to identify network alterations that explain phosphorylation dynamics of the MEK/ERK module in response to hepatocyte growth factor or inte...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080803 | MassIVE
ProteomicsChemical and phosphoproteomics illuminate the cellular mode of action of AKT inhibitors
Due to its key role in dysregulated cellular signaling in cancer, AKT has been subject to intense drug discovery efforts leading to small molecule inhibitors investigated in clinical trials, notably breast cancer. To shed more light on how these drugs exert their therapeutic effects, we integrated c...
ORGANISM(S): Homo Sapiens 
2022-01-21 | PXD015188 | panorama
UnknownInfluence of hunting strategy on foraging efficiency in Galapagos sea lions.
Not available
S-EPMC8051337 | biostudies-literature
UnknownRisk of strong antibody decline in dialysis and transplant patients after SARS-CoV-2mRNA vaccination: Six months data from the observational Dia-Vacc study.
Not available
S-EPMC8995854 | biostudies-literature
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