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ProteomicsSialic acid-mediated mechanical activation of β2 adrenergic receptors by bacterial pili
Meningococcus utilizes β-arrestin selective activation of endothelial cell β2 adrenergic receptor (β2AR) to cause meningitis in humans. Molecular mechanisms of receptor activation by the pathogen and of its species selectivity remained elusive. We report that β2AR activation requires two asparagine-...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD015389 | Pride
Proline effect Human β-adrenergic receptor Pilin Q-exactive Blood-brain barrier Internal fragments N-glycan 
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