Mass defect - OmicsDI

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Unknown (933)
Proteomics (386)
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Models (1)
Methylation profiling (1)

Organisms

Homo sapiens (265)
Mus musculus (173)
Saccharomyces cerevisiae (34)
Drosophila melanogaster (25)
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Rattus norvegicus (16)
Arabidopsis thaliana (12)
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Bacillus subtilis subsp. subtilis str. 168 (3)
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human gut metagenome (1)
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Euphausia superba (1)

Organisms

Mus musculus (23)
Homo sapiens (12)
Rattus norvegicus (2)
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Paramecium tetraurelia (1)
Canis lupus (1)
Candida albicans (1)
Pseudomonas aeruginosa (1)
Drosophila melanogaster (1)

Repository

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Tissue

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Disease

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Sanfilippo syndrome type B (1)
Unilateral congenital transverse defect of his right upper (absence of forearm and hand) and right lower (absence of foot) limbs; a high platelet count (1)
IRAK-4 Q293X mutation (1)
Type 1 Diabetes Mellitus (1)
T-cell acute lymphoblastic leukemia (1)
Normal (1)
3-methylglutaconic aciduria type 9 (1)
Abnormal breast morphology (1)
Albright's hereditary osteodystrophy (1)
Alpha 1-antitrypsin deficiency (1)
Atopic dermatitis (1)
Autoimmune lymphoproliferative syndrome (1)
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Technology Type

Mass Spectrometry (288)
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Mass spectrometry (83)
Bottom-up proteomics (59)
Mass spectrometry assay (51)
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Data-dependent acquisition (26)
Gel-based experiment (24)
Data-independent acquisition (12)
SWATH MS (8)
Top-down proteomics (7)
All-ion fragmentation (5)
Chemical cross-linking coupled with mass spectrometry proteomics (5)
NMR spectroscopy (3)
DiaPASEF (2)
Illumina HiSeq 2000 (1)
NMR spectroscopy assay (1)
Affinity proteomics (1)
HDMSE (1)
Immunopeptidomics (1)
Mass spectrometry imaging (1)
SRM/MRM (1)

Instrument Platform

Orbitrap Fusion Lumos (13)
Q Exactive (11)
Illumina HiSeq 4000 (9)
LTQ Orbitrap Velos (9)
Orbitrap Fusion (9)
Q Exactive HF-X (6)
Illumina NovaSeq 6000 (5)
Orbitrap Exploris 480 (5)
Q Exactive HF (5)
NextSeq 500 (4)
Orbitrap Eclipse (4)
Q Exactive Plus (4)
6560 Q-TOF LC/MS (3)
AB SOLiD 4 System (2)
Chemostat (2)
Affymetrix (2)
Illumina NovaSeq X (2)
Illumina HiSeq 2000 (2)
API 5500 QTRAP (AB Sciex) (2)
Agilent 6560 (2)
LTQ Orbitrap Velos Pro (2)
In Silico Molecular Cloning Program (1)
Agilent G2505B scanner (1)
GenePix 4000B [Axon Instruments] (1)
DNBSEQ-G400 (1)
BGISEQ-500 (1)
NextSeq 550 (1)
Illumina HiSeq 2500 (1)
Agilent 6545 quadrupole time-of-flight mass spectrometer (1)
Thermo Scientific instrument model|1000494 (1)

Publication Date

2026 (91)
2025 (85)
2022 (75)
2024 (70)
2023 (69)
2021 (55)
2020 (53)
2010 (51)
2015 (50)
2013 (37)
2011 (36)
2019 (35)
2012 (34)
2014 (30)
2018 (24)
2016 (22)
2009 (12)
2008 (11)
2017 (8)
2007 (7)
2006 (3)
2005 (3)
2004 (3)

UNIPROT ID/AC

1433E_HUMAN (2)
1433F_HUMAN (2)
1433G_HUMAN (2)
1433S_HUMAN (2)
1433T_HUMAN (2)
1433Z_HUMAN (2)
2A5A_HUMAN (2)
2A5D_HUMAN (2)
2A5E_HUMAN (2)
2A5G_HUMAN (2)
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2AAB_HUMAN (2)
2ABA_HUMAN (2)
2ABD_HUMAN (2)
3HAO_HUMAN (2)
3HIDH_HUMAN (2)
41_HUMAN (2)
4EBP1_HUMAN (2)
4EBP2_HUMAN (2)
4F2_HUMAN (2)
5NT1A_HUMAN (2)
5NT3A_HUMAN (2)
5NTC_HUMAN (2)
5NTD_HUMAN (2)
6PGD_HUMAN (2)
6PGL_HUMAN (2)
8ODP_HUMAN (2)
9606.ENSP00000228938 (2)
P04070 (1)
P12259 (1)

CHEBI ID

CHEBI:16015 (31)
CHEBI:18012 (31)
CHEBI:15756 (30)
CHEBI:17295 (29)
CHEBI:30769 (29)
CHEBI:15428 (28)
CHEBI:17568 (28)
CHEBI:15741 (27)
CHEBI:16857 (26)
CHEBI:17895 (26)
CHEBI:17053 (25)
CHEBI:17203 (25)
CHEBI:16704 (23)
CHEBI:16708 (23)
CHEBI:16958 (23)
CHEBI:17368 (23)
CHEBI:17596 (23)
CHEBI:6650 (23)
CHEBI:16027 (22)
CHEBI:16977 (22)
CHEBI:17754 (22)
CHEBI:28842 (22)
CHEBI:16414 (21)
CHEBI:17115 (21)
CHEBI:30915 (21)
CHEBI:16828 (20)
CHEBI:17196 (20)
CHEBI:17268 (20)
CHEBI:16235 (19)
CHEBI:16335 (19)

Metabolite Name

Uracil (28)
Inosine (27)
Adenine (26)
L-Tyrosine (26)
Hypoxanthine (25)
Adenosine (23)
Guanosine (23)
Uridine (22)
L-Phenylalanine (21)
Xanthine (21)
L-Leucine (20)
L-Tryptophan (20)
Creatinine (19)
Glycine (19)
L-Proline (19)
Taurine (19)
Creatine (18)
Palmitic acid (18)
L-Alanine (17)
L-Isoleucine (17)
L-Serine (17)
Myristic acid (17)
Betaine (16)
Fumaric acid (16)
Guanine (16)
Pantothenic acid (16)
Azelaic acid (15)
Citric acid (15)
Cytidine (15)
L-Aspartic acid (15)

First Public Date

2026 (12)
2024 (11)
2023 (5)
2025 (4)
2022 (3)
2019 (3)
2015 (3)
2020 (2)
2014 (2)
2021 (1)
2018 (1)
2017 (1)
2016 (1)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Lomonosov Moscow State University (4)
Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada K1H 8M5 (3)
Institut Pasteur Unité "Plasticité du Génome Bactérien" Département Génomes et Génétique 28 rue du Docteur Roux 75724 Paris Cedex 15 (3)
Max Planck Institute for Terrestrial Microbiology Karl-von-Frisch Str. 10 35043 Marburg Germany (3)
College of Life Sciences, South-Central University for Nationalities (2)
Department of Biosciences, University of Oslo, P.O. Box 1066 Blindern, 0316 Oslo, Norway (2)
Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy (2)
Director, Translational Proteomics Research Unit, IRCM Director, Biomarker Pipeline for Precision Medicine Strategic Initiative Full IRCM Research Professor Full Research Professor, Department of Biochemistry and Molecular Medicine (accreditation for the Molecular Biology Programs), Université de Montréal Holder of the Bell-Bombardier Chair of Excellence Person in charge of responsible conduct of research, IRCM (2)
EDyP (2)
Functional Proteomics, ICR (2)
Head of Proteomics (2)
Institute of Biochemistry II Goethe University Frankfurt – Medical School University Hospital Germany (2)
Proteomics Core Facility and Research Group Proteomics, CEITEC-MU, Masaryk University, Brno, Czech Republic (2)
Proteomics program, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark (2)
Southwest University (2)
The University of Melbourne (2)
Université Paris-Saclay, INRAE, AgroParisTech, GABI, 78350, Jouy-en-Josas, France (2)
(1) Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK; (2) Leibniz-Institute für Analytische Wissenschaften-ISAS- e.V., Dortmund, Germany (1)
-The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, Victoria 3052, Australia. -Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010, Australia. (1)
1 Department of Convergence Medicine, Asan Institute for Life Sciences, Asan Medical Center, Seoul 05505, Republic of Korea 2 Department of Biomedical Sciences, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea 3 Clinical Proteomics Core Laboratory, Convergence Medicine Research Center, Asan Medical Center, Seoul 05505, Republic of Korea 4 Bio-Medical Institute of Technology, Asan Medical Center, Seoul 05505, Republic of Korea (1)
1 Hudson Institute of Medical Research, Clayton, VIC, Australia, 2 Department of Molecular and Translational Sciences, Monash University, Clayton, VIC, Australia (1)
1 The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Denmark 2 Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark 4 Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark (1)
1) Department Preclinical Development and Validation, Fraunhofer Institute for Cell Therapy and Immunology IZI, Leipzig, Germany; 2) Institute for Bioanalysis, University of Applied Science Coburg, Coburg, Germany (1)
1. Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany 2. Pediatric Neurology, University Hospital Essen, University of Duisburg-Essen, Faculty of Medicine, Essen, Germany (1)
1Center for Medical Genetics, Ghent University Hospital, Ghent, 9000, Belgium 2Department of Biomolecular Medicine, Faculty of Medicine and Health Sciences, Ghent (1)
1Department of Microbiology, University of Washington, Seattle, Washington, USA (1)
1The First Department of Clinical Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, Fujian Province, China. 2Medical Genetic Diagnosis and Therapy Center of Fujian Maternity and Child Health Hospital, College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fujian Provincial Key Laboratory of Prenatal Diagnosis and Birth Defects, Fuzhou 350001, Fujian Province, China. (1)
4The Novo Nordisk Foundation Center for Protein Research, Clinical Proteomics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. (1)
Aix-Marseille Univ, CNRS, FR3479, Proteomics facility of Institut de Microbilogie de la Méditerranée, Marseille Protéomique (1)
Associate Professor of Biochemistry Schulich School of Medicine and Dentistry Scientist, Children’s Health Research Institute (CHRI) Medical Sciences Building 358 Western University London, Ontario N6A 5C1, Canada (1)

IsPrivate

False (1)

Classification

bacteria (1)
fungi (1)

Study type

Transcription profiling by array (159)
RNA-seq of coding RNA (39)
ChIP-seq (22)
ChIP-chip by tiling array (17)
Unknown experiment type (9)
Comparative genomic hybridization by array (9)
Transcription profiling by RT-PCR (6)
Other (5)
ChIP-chip by array (4)
DNA-seq (4)
RNA-seq of coding RNA from single cells (4)
Methylation profiling by high throughput sequencing (4)
Animal - High-throughput sequencing (3)
Transcription profiling by tiling array (3)
Genotyping by array (3)
Cell line - High-throughput sequencing (2)
Proteomic profiling by mass spectrometer (2)
Methylation profiling by array (2)
RNA-seq of non coding RNA (2)
Cell line - One-color microarray (1)
Bisulfite-seq (1)
RIP-seq (1)
RNA-seq of total RNA (1)

Release Date

2021 (103)
2022 (102)
2023 (101)
2025 (88)
2024 (80)
2020 (74)
2010 (73)
2015 (71)
2019 (66)
2013 (58)
2011 (57)
2014 (56)
2017 (54)
2016 (53)
2012 (52)
2018 (49)
2009 (21)
2008 (17)
2026 (11)
2007 (11)
2006 (10)
2001 (8)
2005 (7)
2004 (4)
2002 (4)
1998 (2)
2003 (1)
2000 (1)
1999 (1)
1991 (1)

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Differentiation Defect Repositions Sebaceous Glands as Instigators in the Early Pathogenesis of Hidradenitis Suppurativa

The role of sebaceous glands (SGs) in the early pathogenesis of hidradenitis suppurativa (HS) is undefined, with unclear causal relationship to inflammatory sequelae. The aim of this study was to determine whether SG aberrations constitute a primary pathogenic driver in early HS and elucidate the...

2025-12-28 | MTBLS13578 | MetaboLights

CRISPR-Cas9 knockout of WS1A/WS1B alleviates postharvest green vein defect via tissue-specific chloroplast degradation in flue-cured tobacco

This dataset contains tissue-resolved untargeted metabolome data from flue-cured tobacco cultivar Honghuadajinyuan (wild-type) and transgene-free ws1 mutants generated by CRISPR-Cas9 knockout of homeologous WS1A/WS1B. Multiple tobacco tissues were profiled to capture metabolite alterations triggered...

2026-10-10 | MTBLS15979 | MetaboLights

Mass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism

Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with 50-80% patients exhibiting mutations in the von Hippel-Lindau (VHL) gene. RSUME (RWD domain (termed after three major RWD-containing proteins: RING finger-containing proteins, WD-repeat-containing proteins, and yeast DEAD (DEXD)...

2021-10-06 | MTBLS1935 | MetaboLights

Coupled Mass-Spectrometry-Based Lipidomics Machine Learning Approach for Early Detection of Clear Cell Renal Cell Carcinoma

A discovery-based lipid profiling study of serum samples from a cohort that included patients with clear cell Renal Cell Carcinoma (ccRCC) stage I, II, III, and IV (n=112) and controls (n=52) was performed using ultraperformance liquid chromatography coupled to quadrupole-time-of-flight mass spec...

2020-11-20 | MTBLS1839 | MetaboLights

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

Human brain organoids are emerging models to study human brain development and pathology as they recapitulate the development and characteristics of major neural cell types, and enable manipulation through an in vitro system. Over the past decade, with the advent of spatial technologies,...

2023-05-23 | MTBLS7565 | MetaboLights

MALDI SpiralTOF high-resolution mass spectrometry and Kendrick mass defect analysis applied to the characterization of poly(ethylene-co-vinyl acetate) copolymers.

Not available

S-EPMC4787217 | biostudies-literature

Mass defect filtering for suspect screening of halogenated environmental chemicals: A case study of chlorinated organophosphate flame retardants.

Not available

S-EPMC9375139 | biostudies-literature

Improving the Resolution of Kendrick Mass Defect Analysis for Polymer Ions with Fractional Base Units.

Not available

S-EPMC5447562 | biostudies-literature

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) reveals potential lipid markers between infrapatellar fat pad biopsies of osteoarthritis and cartilage defect patients.

Not available