Mass photometry

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1. Laboratoire de Spectrométrie de Masse BioOrganique, IPHC UMR 7178, Université de Strasbourg, CNRS, 67000 Strasbourg, France 2. Infrastructure Nationale de Protéomique ProFI – FR2048, 67087 Strasbourg, France (1)
1. Laboratoire de Spectrométrie de Masse BioOrganique, IPHC UMR 7178, Université de Strasbourg, CNRS, 67000 Strasbourg, France 2. Infrastructure Nationale de Protéomique ProFI – FR2048, 67087 Strasbourg, France (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, University of Utrecht (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences,University of Utrecht (1)
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Professor, Molecular Medicine, Wertheim UF Scripps, USA (1)
ProteoToul, Institute of Pharmacology and Structural Biology (IPBS), CNRS, Toulouse (1)
UNIVERSITY OF OXFORD, DIVISION OF STRUCTURAL BIOLOGY (1)

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Denaturing mass photometry for rapid optimization of chemical protein-protein cross-linking reactions

Chemical cross-linking reactions (XL) are an important strategy for studying protein-protein interactions (PPIs), including low abundant sub-complexes, in structural biology. However, choosing XL reagents and conditions is laborious and mostly limited to analysis of protein assemblies that can be re...

ORGANISM(S): Escherichia coli

2024-03-15 | PXD042549 | Pride

Mass photometry Cross-linking mass spectrometry

Single-particle mass analysis of intact ribosomes by mass photometry and Orbitrap-based charge detection mass spectrometry.

Not available

S-EPMC8529500 | biostudies-literature

Single molecule mass photometry of nucleic acids.

Not available

S-EPMC7515692 | biostudies-literature

Characterization of intact mRNA-based therapeutics by charge detection mass spectrometry and mass photometry.

Not available

S-EPMC11999443 | biostudies-literature

Lifting the Concentration Limit of Mass Photometry by PEG Nanopatterning.

Not available

S-EPMC11342371 | biostudies-literature

Revealing the effect of SARS-CoV-2 spike stabilisation on receptor binding dynamics with single molecule mass photometry

Here we show using mass photometry how proline substitutions, commonly used for SARS-CoV-2 spike stabilisation and vaccine design, directly impedes ACE2 receptor interactions via dynamics of open and closed states. Conformational changes and ACE2 binding were influenced by spike variant and temperat...

ORGANISM(S): Homo sapiens (Human)

2023-06-28 | PXD036289 | Pride

Sars-cov-2 Glycomics Spike Glycoproteomics Mass photometry Ace2

Breaking barriers in the sensitive and accurate mass determination of large DNA plasmids by mass photometry.

Not available

S-EPMC12328894 | biostudies-literature

Quantifying the Monomer-Dimer Equilibrium of Tubulin with Mass Photometry.

Not available

S-EPMC7763485 | biostudies-literature

Quantifying Protein-Protein Interactions by Molecular Counting with Mass Photometry.

Not available

S-EPMC7318626 | biostudies-literature