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ProteomicsHs_CancerTissue_MembraneProteomic
In-depth membrane proteomic study of breast cancer tissues
ORGANISM(S): Homo Sapiens (human) 
2013-12-31 | PAe004084 | PeptideAtlas
ProteomicsMembrane proteomic analysis of colorectal cancer tissue
We performed shotgun proteomics of colorectal cancer tissue and premalignant lesions using iTRAQ to identify biomarker candidate proteins for colorectal cancer.
ORGANISM(S): Homo sapiens (Human) 
2014-04-02 | PXD000851 | Pride
Human Membrane protein Colorectal cancer 
TranscriptomicsDevelopment of gene expression profiles in human chronic kidney disease
A microarray analysis with renal biopsy specimens from CKD patients was conducted in order to identify the responsible genes associated with tubulointerstitial fibrosis and tubular cell injury in CKD. This study showed microarray profiles in total 53 biopsy specimens of CKD patients. In the discover...
ORGANISM(S): Homo sapiens 
2015-08-16 | E-GEOD-66494 | biostudies-arrayexpress
OtherDiscovery of colorectal cancer biomarker candidates by membrane proteomic analysisand subsequent verification using selected reaction monitoring and tissue microarrayanalysis
Data from ProteomeXchange, PXD ID: PXD000851. File: iTRAQ3.msf.mgf. Published as part of Mol Cell Proteomics. 2014 Mar 31 . From the Abstract: {{i}} We here performed a quantitative proteomic analysis of membrane fractions from colorectal cancer tissue to discover biomarker candidates, and then ext...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM11210027051 | GPMDB
Resource Reanalysis 
ProteomicsProteome study to optimize Zeno SWATH DIA
Data-independent acquisition (DIA) techniques, such as SWATH acquisition, have emerged as the preferred strategy for proteomic analysis. Our study optimizes the SWATH-DIA method using a narrow isolation window placement approach improving its proteomic performance. We optimized the acquisition param...
ORGANISM(S): Homo Sapiens (human) Cellular Organisms Mus Musculus (mouse) 
2024-07-20 | PXD050030 | JPOST Repository
ProteomicsBrain microvascular endothelial cells: PODXL KD
The purpose of the present study was, therefore, to explore the effect of PODXL-knockdown on the protein expression and transport function in the immortalized human BMECs (hCMEC/D3) as a human BBB model. We established PODXL-knockdown hCMEC/D3 cells, and protein expressions were comprehensively anal...
ORGANISM(S): Homo Sapiens (human) 
2022-03-11 | PXD030652 | JPOST Repository
ProteomicsProteomic study of the mice treated with antibiotics
Antibiotic administration affects pharmacokinetics through changes in the intestinal microbiota, and bile acids are involved in this regulation. The purpose of the present study was to clarify the effect of different periods of antibiotic administration on the expression of pharmacokinetic-related p...
ORGANISM(S): Mus Musculus (mouse) 
2023-07-12 | PXD037296 | JPOST Repository
ProteomicsMBEC4 cells with low-Arginine conditions
Amino acid transporters are expressed in the brain capillary endothelial cells, which form the blood-brain barrier, and their expression levels change during the neonatal period. This study aimed to investigate the molecular mechanisms regulating the amino acid transporter levels in mouse brain capi...
ORGANISM(S): Mus Musculus (mouse) 
2025-04-11 | PXD054477 | JPOST Repository
ProteomicsBrain microvascular endothelial cells: INSR KD
The insulin receptor (INSR) mediates insulin signaling to modulate cellular functions. Although INSR is expressed at the blood-brain barrier (BBB), its role in the modulation of BBB function is poorly understood. Therefore, in this study, we aimed to analyze the effect of INSR knockdown on the expre...
ORGANISM(S): Homo Sapiens (human) 
2021-12-25 | PXD027326 | JPOST Repository
ProteomicsDigestion time course of human liver plasma membrane
The selection of signature peptides is critical for reliable peptide quantification. The purpose of this study was to comprehensively assess the digestion efficiency and stability of tryptic peptides and to identify optimal signature peptides for human hepatic transporters and membrane marker protei...
ORGANISM(S): Homo Sapiens (human) 
2022-10-12 | PXD034402 | JPOST Repository
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