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ProteomicsCharacterization of novel human cystatin B salivary interactome in Alzheimer’s disease and healthy subjects.
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the elderly, characterized by the accumulation in the brain of misfolded proteins, inflammation, and oxidative damage leading to neuronal cell death. The necessity of searching for new non-invasive biomarkers in tissues or b...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD030679 | Pride
Coip Proteomics Alzheimer Cystatinb Lc-msms Interactome 
ProteomicsCharacterization of novel human cystatin B salivary interactome in Alzheimer’s disease and healthy subjects.
Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease in the elderly, characterized by the accumulation in the brain of misfolded proteins, inflammation, and oxidative damage leading to neuronal cell death. The necessity of searching for new non-invasive biomarkers in tissues or b...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD039286 | Pride
Coip Proteomics Alzheimer Cystatinb Lc-msms Interactome 
ProteomicsTop-down proteomics of human saliva in Alzheimer disease
Alzheimer disease (AD) is the most prevalent neurodegenerative disease and form of dementia in the elderly. It is characterized by the accumulation in the brain of misfolded proteins, inflammation and oxidative damage leading to region-specific loss of synaptic contacts and neuronal cell death. In t...
ORGANISM(S): Homo sapiens (Human) 
2021-05-24 | PXD021538 | Pride
S100a Salivary proteomics Alzheimer disease Oxidative stress Cystatins Α-defensins Antimicrobial peptides Thymosin β4 
ProteomicsA top-down proteomic approach reveals a salivary protein profile classifying Parkinson’s disease with respect to Alzheimer’s disease patients and to healthy controls
Parkinson’s disease (PD) is a complex neurodegenerative disease (ND) with heterogeneous clinical conditions, including progressive motor and non-motor symptoms and cognitive impairment, because of the loss of dopaminergic and serotoninergic neurons across the brain. Brain tissue and CSF are elective...
ORGANISM(S): Homo sapiens (Human) 
2026-10-05 | PXD041787 | Pride
Top-down proteomics Salivary proteomics Lc-ms Neurodegeneration Parkinson disease 
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