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ProteomicsOptimizing MS-based multi-omics: comparative analysis of protein, metabolite, and lipid extraction techniques
Multi-omics integrates diverse types of biological information from genomic, proteomic, and metabolomics experiments to achieve a comprehensive understanding of complex cellular mechanisms. However, this approach is also challenging due to technical issues such as limited sample quantities, complex...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD047010 | Pride
Lc-ms Fasp Matyash method S-trap Multi-omics Folch method 
ProteomicsComparative analysis of three extraction method for simultaneous metabolomic and proteomic profiling
The simultaneous analysis of the proteome and metabolome in biological samples is essential for advancing systems biology, enabling a deeper understanding of molecular mechanisms governing diverse biological processes. This study compares three extraction methods: the Bligh and Dyer method, the Maty...
ORGANISM(S): Solanum tuberosum (Potato) 
2026-02-09 | PXD060367 | Pride
High resolution mass spectrometry Metabolomics Proteomics Potato tubers Starch Multi-omics Extraction methods 
UnknownOptimization of Folch, Bligh-Dyer, and Matyash sample-to-extraction solvent ratios for human plasma-based lipidomics studies.
Not available
S-EPMC6261534 | biostudies-literature
MetabolomicsComprehensive lipid analysis of green Arabica coffee beans by LC-HRMS/MS
Lipids play an important role in coffee bean development, coffee brew and in the effects of coffee on human health. They account for around 17% of the dry bean weight and encompass different classes and subclasses, mostly triacylglycerols (TAG) and a minor quantity of phospholipids (PL) and βN-alkan...
2021-11-19 | MTBLS1972 | MetaboLights
UnknownA method to measure molecular hybridization.
Not available
S-EPMC11329138 | biostudies-literature
UnknownComparison of blood plasma sample preparation methods for combined LC-MS lipidomics and metabolomics.
Not available
S-EPMC4582001 | biostudies-literature
ProteomicsMZmine3_Nature_Protocol_Lipids_Dataset
Sheep brain samples extracted with methyl-tert-butyl (Matyash protocol) and analysed by HILIC-IMS-MS.
ORGANISM(S): Ovis Aries (ncbitaxon:9940) 
2023-04-04 | MSV000091633 | MassIVE
ProteomicsMZmine3_Nature_Protocol_Lipid_Dataset
Sheep brain samples extracted with methyl-tert-butyl ether (Matyash protocol) and analysed by HILIC-IMS-MS.
ORGANISM(S): Ovis Aries (ncbitaxon:9940) 
2023-04-04 | MSV000091642 | MassIVE
UnknownComparing the Extraction Performance in Mouse Plasma of Different Biphasic Methods for Polar and Nonpolar Compounds.
Not available
S-EPMC11301682 | biostudies-literature
UnknownRapid Multi-Omics Sample Preparation for Mass Spectrometry.
Not available
S-EPMC10026941 | biostudies-literature
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