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MetabolomicsNMR-Based Metabolomics of Non-Human Primate Ocular Tissues: A Dataset
Model animals are employed in experiments as substitutes for human tissues and fluids, particularly when accessing particular human samples (such as cerebrospinal fluid, brain, ocular tissues, etc.) poses significant challenges or is ethically constrained. Nonhuman primates are frequently regarded a...
2023-11-16 | MTBLS8943 | MetaboLights
TranscriptomicsMicroarray study of human adrenal zona glomerulosa (ZG), zona fasciculata (ZF) and aldosterone-producing adenomas (APA)
Learn about the transcriptome profiling of zona glomerulosa (ZG), zona fasciculata (ZF) and aldosterone-producing adenomas (APA) in human adrenals 21 pairs of zona fasciculata (ZF) and zona glomerulosa (ZG), and 14 paired aldosterone-producing adenomas (APAs) from 14 Conn’s syndrome patients and 7 p...
ORGANISM(S): Homo sapiens 
2015-09-15 | E-GEOD-64957 | biostudies-arrayexpress
UnknownParenteral anticoagulation may prolong the survival of patients with limited small cell lung cancer: a Cochrane systematic review.
Not available
S-EPMC2438335 | biostudies-literature
ProteomicsAge-Related Disruption of the Proteome and Acetylome in Mouse Hearts Correlates with Differential Loss of Function that is Attenuated by SS-31 and NMN
We analyzed the effects of aging on protein abundance and acetylation, as well as the ability of the mitochondrial-targeted drugs SS-31 and NMN to reverse age-related changes, in mouse hearts. Both drugs had a modest effect on restoring the abundance and acetylation of proteins that are lost with ag...
ORGANISM(S): Mus Musculus 
2022-08-02 | PXD027458 | panorama
ProteomicsSortilin Drives Valvular Interstitial Cells to a Combined Inflammatory Myofibroblast-Osteogenic Phenotype in Calcific Aortic Valve Disease as Revealed by Single-cell Analysis
Background: Calcific aortic valve disease (CAVD), the most common valve disease is comprised of a chronic interplay of inflammation, fibrosis, and calcification. In this study, sortilin (SORT1) was identified as a novel key player in the pathophysiology of CAVD, and its role in the transformation of...
ORGANISM(S): Homo sapiens (Human) 
2024-01-03 | PXD038117 | Pride
Calcification Aortic stenosis Sortilin Inflammation Single-cell rna sequencing Fibrosis 
ProteomicsDiversity of cationic antimicrobial peptides in black cumin (Nigella sativa L.) seeds
Black cumin (Nigella sativa L.) is known to possess a wide variety of antimicrobial peptides belonging to different structural families. Three novel antimicrobial peptides have been isolated from black cumin seeds. Two of them were attributed as members of the non-specific lipid transfer proteins fa...
ORGANISM(S): Nigella sativa 
2023-07-20 | PXD040611 | Pride
Defensin Lipid transfer protein (ltp) Antimicrobial peptide (amps) Proteomic analysis Antimicrobial activity 
MetabolomicsMass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism
Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with 50-80% patients exhibiting mutations in the von Hippel-Lindau (VHL) gene. RSUME (RWD domain (termed after three major RWD-containing proteins: RING finger-containing proteins, WD-repeat-containing proteins, and yeast DEAD (DEXD)...
2021-10-06 | MTBLS1935 | MetaboLights
TranscriptomicsExpression of ATHB17 in Maize Increases Ear Weight at Silking
Transformation of the Arabidopsis ATHB17 gene into maize results in the expression of a truncated protein (smaller by 113 amino acids) that functions as a dominant-negative regulator that can modify activity of endogenous maize HD-Zip II transcription factors. This RNASeq experiment indicates that t...
ORGANISM(S): Zea mays 
2015-10-26 | E-GEOD-51742 | biostudies-arrayexpress
UnknownIdentification of Modulators of the C. elegans Aryl Hydrocarbon Receptor and Characterization of Transcriptomic and Metabolic AhR-1 Profiles.
Not available
S-EPMC9137885 | biostudies-literature
UnknownThe effect of alternative summary statistics for communicating risk reduction on decisions about taking statins: a randomized trial.
Not available
S-EPMC2724738 | biostudies-literature
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