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TranscriptomicsComprehensive Characterization of 3D Models for Prostate Cancer Growth and Invasion in Laminin-rich Extracellular Matrix
Full title: Comprehensive Characterization of Three-Dimensional Models for Prostate Cancer Growth and Invasion in Laminin-rich Extracellular Matrix Prostate Cancer (PrCa) cells undergo acinar morphogenesis and spheroid formation in three-dimensional (3D) culture, supported by laminin-rich extracellu...
ORGANISM(S): Homo sapiens 
2010-12-06 | E-GEOD-19426 | biostudies-arrayexpress
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
UnknownTargeting interleukin-6 as a treatment approach for peritoneal carcinomatosis.
Not available
S-EPMC11061933 | biostudies-literature
ProteomicsHuman CSF peptidomics of gamma secretase inhibition
Fifteen human healthy volunteers, divided into three groups, received a single dose of placebo or either 140 mg or 280 mg of the ?-secretase inhibitor semagacestat (LY450139). Endogenous peptides in CSF, sampled prior to administration of the drug and at six subsequent time points, were analyzed by ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080870 | MassIVE
UnknownIdentification and characterisation of a novel adhesin Ifp in Yersinia pseudotuberculosis.
Not available
S-EPMC3102037 | biostudies-literature
UnknownThe MIT domain of chitin synthase 1 from the oomycete Saprolegnia monoica interacts specifically with phosphatidic acid.
Not available
S-EPMC8851075 | biostudies-literature
GenomicsTDP-1, the C. elegans ortholog of TDP-43, limits the accumulation of double stranded RNA
C. elegans mutants deleted for TDP-1, an ortholog of the neurodegeneration-associated RNA binding protein TDP-43, display only mild phenotypes. Nevertheless, transcriptome sequencing revealed that many RNAs were altered in accumulation and/or processing in the mutant. Analysis of these transcription...
ORGANISM(S): Caenorhabditis elegans 
2014-11-19 | E-GEOD-61581 | biostudies-arrayexpress
TranscriptomicsGenomewide demarcation of RNA PolII transcription units by physical fractionation of chromatin- ALL Arrays
Epigenetic modifications of chromatin serve an important role in regulating the expression and accessibility of genomic DNA. We report here a genomewide approach for fractionating yeast chromatin into two functionally distinct parts, one containing RNA polymerase II transcribed sequences, and the ot...
ORGANISM(S): Saccharomyces cerevisiae 
2006-08-30 | E-GEOD-5662 | biostudies-arrayexpress
TranscriptomicsGenomewide demarcation of RNA PolII transcription units by physical fractionation of chromatin- Intergenic enrichment
Epigenetic modifications of chromatin serve an important role in regulating the expression and accessibility of genomic DNA. We report here a genomewide approach for fractionating yeast chromatin into two functionally distinct parts, one containing RNA polymerase II transcribed sequences, and the ot...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-01 | E-GEOD-5648 | biostudies-arrayexpress
UnknownCell-Type-Specific Translation Profiling Reveals a Novel Strategy for Treating Fragile X Syndrome.
Not available
S-EPMC5548955 | biostudies-literature
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