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GenomicsLigand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating Retinoic Acid Receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presence of the ret...
ORGANISM(S): Mus musculus 
2010-12-10 | E-GEOD-19409 | biostudies-arrayexpress
ProteomicsSemaglutide exerts stronger cardioprotective effects than caloric restriction in mice with HFpEF
Patients with heart failure with preserved ejection fraction (HFpEF) often have an unfavorable cardiometabolic profile, and obesity-related HFpEF has become a well-recognized HFpEF sub-phenotype. Targeting this unfavorable cardiometabolic profile may therefore represent a rational treatment strategy...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD034625 | Pride
Hfpef Plasma Heart Proteomics Cardioprotection Semaglutide 
UnknownAir bronchogram integrated lung ultrasound score to monitor community-acquired pneumonia in a pilot pediatric population.
Not available
S-EPMC7787130 | biostudies-literature
GenomicsCTCF functions as a chromatin insulator in the HoxA cluster during neurogenesis [ChIP-Seq]
In this experiment, we sought to identify how the distribution of CTCF, H3K27me3, H3K4me3, Pol II, H2AK119Ub1, EZH2 3 lines (WT, Δ5|6, Δ5|6:7|9)
ORGANISM(S): Mus musculus 
2015-02-26 | E-GEOD-60232 | biostudies-arrayexpress
GenomicsInduced Cdx2 binding in embryonic stem cells and endodermal cells
Regulatory proteins can bind to different sets of genomic targets in various cell types or conditions. To reliably characterize such condition-specific regulatory binding we introduce MultiGPS, an integrated machine learning approach for the analysis of multiple related ChIP-seq experiments. MultiGP...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-39435 | biostudies-arrayexpress
TranscriptomicsCTCF functions as a chromatin insulator in the HoxA cluster during neurogenesis [RNA-Seq]
In this experiment, we sought to analyze how the transcriptome of WT, Δ5|6, and Δ5|6:7|9 cells vary during differentiation of ESCs into cervical motor neurons 3 lines (WT, Δ5|6, Δ5|6:7|9)
ORGANISM(S): Mus musculus 
2015-02-26 | E-GEOD-60226 | biostudies-arrayexpress
UnknownDo It by Yourself: Larval Locomotion in the Black Soldier Fly Hermetia illucens, with a Novel "Self-Harvesting" Method to Separate Prepupae.
Not available
S-EPMC8879302 | biostudies-literature
TranscriptomicsCTCF functions as a chromatin insulator in the HoxA cluster during neurogenesis [4C-Seq]
In this experiment, we sought to analyze how the spatial organization of WT, Δ5|6, and Δ5|6:7|9 cells vary during differentiation of ESCs into cervical motor neurons 3 lines (WT, Δ5|6, Δ5|6:7|9)
ORGANISM(S): Mus musculus 
2015-02-26 | E-GEOD-60227 | biostudies-arrayexpress
GenomicsHoxc9 ChIP-seq in differentiating motor neurons
The expression of v5-tagged Hoxc9 is induced and ChIP-seq is used to profile genome-wide occupancy in differentiating motor neurons The differentiation of ventral motor neurons is induced by treating embryonic stem cell cultures with retinoic acid and hedgehog signaling. Here, ChIP-seq is used to pr...
ORGANISM(S): Mus musculus 
2010-09-08 | E-GEOD-21812 | biostudies-arrayexpress
UnknownIdentification of ligand and receptor interactions in CKD and MASH through the integration of single cell and spatial transcriptomics.
Not available
S-EPMC11104622 | biostudies-literature
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