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ProteomicsMulti-Enzymatic Limited Digestion - the Next-Generation Sequencing for Proteomics
An innovative approach merging both the bottom-up and middle-down ideologies to provide fast, robust and comprehensive solutions for proteomics studies. The methodology, referred to as MELD for Multiple-Enzymatic Limited Digestion, capitalizes on a single two-hour long proteolytic step involving the...
ORGANISM(S): Homo sapiens (Human) 
2019-05-08 | PXD009800 | Pride
Ptms Digestibility profile Limited digestion Mass spectrometry Proteolytic method Protein characterization De novo sequencing  mabs 
UnknownTumour homing and therapeutic effect of colloidal nanoparticles depend on the number of attached antibodies.
Not available
S-EPMC5187442 | biostudies-literature
UnknownStructure of New Ferroverdins Recruiting Unconventional Ferrous Iron Chelating Agents.
Not available
S-EPMC9221444 | biostudies-literature
UnknownmiR-579-3p controls melanoma progression and resistance to target therapy.
Not available
S-EPMC5003278 | biostudies-literature
UnknownMultivalent exposure of trastuzumab on iron oxide nanoparticles improves antitumor potential and reduces resistance in HER2-positive breast cancer cells.
Not available
S-EPMC5920071 | biostudies-literature
UnknownBisdemethoxycurcumin (BDC)-Loaded H-Ferritin-Nanocages Mediate the Regulation of Inflammation in Alzheimer's Disease Patients.
Not available
S-EPMC9409287 | biostudies-literature
ProteomicsRevisiting Ehrlichia ruminantium Replication Cycle Using Proteomics : The Host and the Bacterium Perspectives
The Rickettsiales Ehrlichia ruminantium (ER), the causal agent of the fatal tick-borne disease Heartwater, induces severe damage to the vascular endothelium in ruminants. Nevertheless, E. ruminantium-induced pathobiology remains largely unknown. Our work paves the way for understanding this phenomen...
ORGANISM(S): Bos taurus (Bovine) Ehrlichia ruminantium str. Gardel 
2021-07-14 | PXD026092 | Pride
Ehrlichia ruminantium  endothelial cells  host response  immunomodulation  bacterial life cycle  differential protein expression  infection biomarkers  virulence factors 
UnknownLevels and effectiveness of oral retinol supplementation in VLBW preterm infants.
Not available
S-EPMC6311539 | biostudies-literature
ProteomicsOsteoarthritis osteoblasts secretome
Osteoarthritis (OA) is the most common joint disease and this is a major cause of joint pain and disability in the aging population. Its etiology is multifactorial (i.e., age, obesity, joint injury, genetic predisposition), and the pathophysiologic process affects the entirety of the joint (Martel-P...
ORGANISM(S): Homo sapiens (Human) 
2018-03-20 | PXD008494 | Pride
Osteoarthritis Secretome Osteoblasts Matrix mineralization Non-collagenous proteins 
UnknownBreast cancer patient-derived organoids for the investigation of patient-specific tumour evolution.
Not available
S-EPMC11210105 | biostudies-literature
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