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TranscriptomicsSingle cell TCR-seq of T cells isolated from MC38 mouse tumors
We investigate the single-cell landscape of the inflammatory mouse tumor model MC38, a C57BL/6 tumor cell line derived from colon adenocarcinoma. MC38 (diluted in HBSS and matrigel) was inoculated in the right unilateral flank (in the border of positions B2 and B3) of C57BL/6 mice (ref Study 16-3384...
ORGANISM(S): Mus musculus 
2019-05-11 | E-MTAB-7918 | biostudies-arrayexpress
TranscriptomicsBulk RNA-Seq analysis of MC38 colon carcinoma cells isolated from Rag2-deficient mice
To assess the role of Bap1 genes in MC38 colon carcinoma cell linewe knocked out the Bap1 gene in the MC38 cell line through CRISPR-Cas9 technology, MC38-Bap1-Wildtype and MC38-Bap1-Knockout tumor cells expressing BFP fluorescent protein were injected into Rag2-deficient mice subcutaneously. On the ...
ORGANISM(S): Mus musculus 
2025-07-06 | E-MTAB-10587 | biostudies-arrayexpress
TranscriptomicsSingle cell TCR-seq profiling of T cells isolated from LNs of MC38 tumor-bearing mice
We investigate the single-cell landscape of the inflammatory mouse tumor model MC38, a C57BL/6 tumor cell line derived from colon adenocarcinoma. MC38 (diluted in HBSS and matrigel) was inoculated in the right unilateral flank (in the border of positions B2 and B3) of C57BL/6 mice (ref Study 16-3384...
ORGANISM(S): Mus musculus 
2022-08-16 | E-MTAB-9734 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq profiling of T cells isolated from MC38 mouse tumors
We investigate the single-cell landscape of the inflammatory mouse tumor model MC38, a C57BL/6 tumor cell line derived from colon adenocarcinoma. MC38 (diluted in HBSS and matrigel) was inoculated in the right unilateral flank (in the border of positions B2 and B3) of C57BL/6 mice (ref Study 16-3384...
ORGANISM(S): Mus musculus 
2019-05-12 | E-MTAB-7919 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq profiling of T cells isolated from LNs of MC38 tumor-bearing mice
We investigate the single-cell landscape of the inflammatory mouse tumor model MC38, a C57BL/6 tumor cell line derived from colon adenocarcinoma. MC38 (diluted in HBSS and matrigel) was inoculated in the right unilateral flank (in the border of positions B2 and B3) of C57BL/6 mice (ref Study 16-3384...
ORGANISM(S): Mus musculus 
2021-02-16 | E-MTAB-9274 | biostudies-arrayexpress
ProteomicsProfiling of tumor-derived extracellular vesicles secreted by genetically MC38 modified cells
In this study exosomal vesicle protein content of genetically modified mouse MC38 colorectal cell lines was assessed. The genetic modifications included overexpression of IL18 and shRNA silencing of IL-10 or TGF-β in following combinations: IL18 overexpression, IL10 silencing, IL10 silencing and IL1...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-05 | PXD066491 | Pride
Extracellular vesicles lfq proteomics mtevs evs dcs dendritic cells mc38 tgfb1 il18 il10 
TranscriptomicsBulk RNA-Seq analysis of MC38 colon carcinoma cells and MC38 Bap1-knockout cells in vitro
In order to find out which genes Bap1 regulates to affect the anti-tumor immune response in MC38 colon carcinoma cell linewe knocked out the Bap1 gene in the MC38 cell line through CRISPR-Cas9 technology, RNA was directly isolated for RNA seq and were able to investigate gene expression.
ORGANISM(S): Mus musculus 
2025-07-06 | E-MTAB-10588 | biostudies-arrayexpress
TranscriptomicsSingle-cell RNAseq of CD45 positive cells in MC38 tumors - Primary irradiated tumors and secondary non-irradiated tumors - Concurrent treatment with anti-PD-L1
Primary irradiated MC38 tumors and secondary MC38 non-irradiated tumors. Subcutaneous MC38 tumors in C57BL/6 mice Concurrent treatment with anti-PD-L1.
ORGANISM(S): Mus musculus 
2023-10-15 | E-MTAB-13389 | biostudies-arrayexpress
GenomicsSingle-cell RNA-seq of MC38 tumor model
Single-cell RNA-seq of MC38 tumor model
PRJEB82211 | ENA
ProteomicsImmunopeptidome on MC38 Cell line
PTM – driven antigenicity – immunopeptidome of MC38 cell line
ORGANISM(S): Mus musculus (Mouse) 
2022-10-12 | PXD017448 | Pride
Ptm Immunopeptidome 
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