Expression profiling of wild-type plants and mutants with defects in key components of the defense signaling network was used to model the Arabidopsis network 24 hours after infection by Pseudomonas syringae pv. maculicola strain Psm ES4326. Results using the Affymetrix ATH1 array revealed that expr...
The cardioprotective effects of long chain (LC) 3PUFA can be achieved at the gene expression level, notably in liver. However, the complexity of biological pathways modulations and the nature of the bioactive molecules are still under investigation. The present study aimed to investigate the dose-re...
RNA-DNA hybrids are widespread epigenetic features of genomes that provide a growing range of activities in transcription, chromatin and DNA replication and repair. Understanding of these diverse functions has been advanced by characterising the proteins that interact with the hybrids, with all such...
The Murphy Roth Large (MRL) mouse, a strain capable of regenerating right ventricular myocardium, has a high post-myocardial infarction (MI) survival rate compared with C57BL6/J (C57) mice. The biological processes responsible for this survival advantage are unknown. We compared acute post-MI gene e...
This a model from the article:
Modeling beta-adrenergic control of cardiac myocyte contractility in silico.
Saucerman JJ, Brunton LL, Michailova AP, McCulloch AD. J Biol Chem
2003 Nov 28;278(48):47997-8003 12972422
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Abstra...
Determine the relative abundance of proteins that associate with DDR1 when cells with different expression levels of DDR1 and lacking beta 1 integrins are cultured on collagen or on fibronectin
