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Cancer stem cells (CSCs) are reported to be responsible for tumor initiation, progression, metastasis, and therapy resistance where P-glycoprotein (P-gp) as well as other glycoproteins are involved. Identification of these glycoprotein markers is critical for understanding the resistance mechanism a...
ORGANISM(S): Homo sapiens (Human) 
2020-02-21 | PXD013836 | Pride
Chemoresistance in breast cancer has been a great interest in past studies, however, the development of rational therapeutic strategies targeting chemoresistant cells is still a challenge for clinical oncology.The resistant property of MCF7/ADR cells was confirmed by long term culture with Dox, cell...
ORGANISM(S): Homo sapiens 
Chemoresistance in breast cancer has been a great interest in past studies, however, the development of rational therapeutic strategies targeting chemoresistant cells is still a challenge for clinical oncology.The resistant property of MCF7/ADR cells was confirmed by long term culture with Dox, cell...
ORGANISM(S): Homo sapiens 
2016-01-05 | GSE76540 | GEO
A major limitation in the cancer treatment is the ability of cancer cells to become resistant to chemotherapeutic drugs, by multidrug establishment. Here, we evaluate the possibility to utilize MC70, either as ABC transporters inhibitor or as anticancer agent, in monotherapy or in combination with d...
ORGANISM(S): Homo sapiens 
This study compares the gene expression level in four cancer cell lines before and after vinigrol treatment. The Lexogen QuantSeq 3'mRNA-seq library kit or Hieff NGS MaxUp II Dual-mode mRNA Library Prep Kit for Illumina MaxUp II was used to prepare the RNA-seq libraries in this study. We identified ...
ORGANISM(S): Homo sapiens 
2022-07-01 | GSE180462 | GEO
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