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TranscriptomicsTranscription profiling of wild type and Ahr(-/-) mouse embryo fibroblast cells
Wildtype vs. Ahr(-/-) mouse embryo fibroblast cells were compared in a flipped-dye design
ORGANISM(S): Mus musculus 
2006-10-17 | E-MEXP-787 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lung from wild type and Mt1(-/-)Mt2(-/-) double knock-out mice after nickel aerosol exposure for 3, 8, 24, 48, and 72 hrs
Wildtype and Mt1(-/-)Mt2(-/-) double knockout 129S1/SvImJ strain mouse lungs were compared in their response to nickel aerosol exposure at 3, 8, 24, 48, and 72 hrs.
ORGANISM(S): Mus musculus 
2006-08-02 | E-MEXP-816 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse aorta and vSMCs response to dioxin
We compared the global gene expression profiles of C57BL/6 mice aortas with the profiles of cultured vascular smooth muscle cells (vSMC) from the same mice, and determined whether gene responses to dioxin exposure in the vSMCs would be predictive of responses in the aorta.
ORGANISM(S): Mus musculus 
2003-10-29 | E-MEXP-23 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse samples of varying RNA concentration amounts and hybridization times on array quality and binding kinetics
Effect of varying RNA concentration amounts and hybridization times on array quality and binding kinetics.
ORGANISM(S): Mus musculus 
2004-03-23 | E-MEXP-40 | biostudies-arrayexpress
TranscriptomicsInfluence of Fatty Acid Diets on Gene Expression in Rat Mammary Epithelial Cells
Background: This study examines the impact of dietary fatty acids on regulation of gene expression in the mammary epithelial cells before and during puberty. Methods: The diets primarily consisted of n-9 monounsaturated fatty acids (olive oil), n-6 polyunsaturated fatty acids (safflower), saturated ...
ORGANISM(S): Rattus norvegicus 
2009-04-01 | E-GEOD-14933 | biostudies-arrayexpress
TranscriptomicsSerpinb3a contributes to early skin inflammation following allergen exposure
Serpinb3a knockout mice show attenuated Transepidermal Water Loss (TEWL) and S100A8 expression (an early inflammatory marker) following treatment with Aspergillus fumigatus extract. The aim of the RNAseq experiments was to provided mechanistic insight for the role of Serpinb3a by identifying early d...
ORGANISM(S): Mus musculus 
2014-10-01 | E-GEOD-54640 | biostudies-arrayexpress
TranscriptomicsEstrogen-driven Prolactin-mediated Gene Expression Networks Hormone Induced Prostatic Dysplasia
Emerging evidence suggests that estrogen and prolactin (PRL) play a key role in prostate cancer development, yet their relationship and molecular actions in prostate is not well understood. To address this issue, we made the first direct comparison of estrogen and PRL actions in the Noble rat (NBL) ...
ORGANISM(S): Rattus norvegicus 
2010-05-09 | E-GEOD-17819 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C3H/HeJ and JF1/Msf strain mice to identify genetic risk factors for asthma and COPD
Comparison of lung function in C3H/HeJ and JF1/Msf strain mice to identify genetic risk factors for asthma and COPD.
ORGANISM(S): Mus musculus 
2007-03-08 | E-MEXP-855 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse T cell sub-populations isolated from pulmonary tissue after mice were exposured to filtered air of acrolein for one week
Mice were exposed to filtered air or acrolein for 1 week. T cell subpopulations were isolated from the pulmonary tissue by cell sorting.
ORGANISM(S): Mus musculus 
2008-11-15 | E-MEXP-1354 | biostudies-arrayexpress
TranscriptomicsMurine: papillary thyroid cancer vs. poorly differentiated thyroid cancer
Mice with thyroid-specific expression of oncogenic BRAF (Tg-Braf) develop papillary thyroid cancers (PTC) that are locally invasive and have well-defined foci of poorly differentiated thyroid carcinoma (PDTC). To investigate the PTC-PDTC progression, we performed a microarray analysis using RNA fro...
ORGANISM(S): Mus musculus 
2011-03-22 | E-GEOD-27668 | biostudies-arrayexpress
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