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ProteomicsLC-MS-Based Quantitative Proteomic Profiling Reveals WWQ-03-012-Induced Alterations in Protein Expression of Human HEL Cells
This experiment employs an analytical platform based on the Ultimate 3000 nano ultra-high-performance liquid chromatography system coupled to the Q Exactive Plus high-resolution mass spectrometer, combined with database search software, to conduct qualitative (or relative quantitative) analysis of p...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD065708 | Pride
Jak2-v617f，human cell，lc-ms 
ProteomicsMass spectrometry analysis identifies DESI2 as a novel component of the JAK2-V617F complex
This experiment employs an analytical platform based on the Ultimate 3000 nano ultra-high-performance liquid chromatography system coupled to the Q Exactive Plus high-resolution mass spectrometer, combined with database search software, to conduct qualitative (or relative quantitative) analysis of p...
ORGANISM(S): Homo sapiens (Human) 
2026-02-09 | PXD065727 | Pride
Jak2-v617f，human cell，lc-ms 
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and opaque2 mutant Transcriptomes
Analysis of gene expression level. The hypothesis tested in the present study was that opaque2 mutant influence the expression of storage proteins. Results provide important information of the gene expression level regulation of storage proteins and other biological processes. Endosperm mRNA profil...
ORGANISM(S): Zea mays 
2014-10-15 | E-GEOD-61830 | biostudies-arrayexpress
MetabolomicsGut microbiota ameliorates hepatic fibrosis through modulating intestinal bile acid metabolism and hepatocyte pyroptosis (Hepatic fibrosis serum+feces)

Parabacteroides distasonis (P. distasonis) plays an important role in human health, including diabetes, colorectal cancer and inflammatory bowel disease. Here, we show that P. distasonis is decreased in patients with hepatic fibrosis, and that administration of P. dista...

2023-03-17 | MTBLS6728 | MetaboLights
MetabolomicsGut microbiota ameliorates hepatic fibrosis through modulating intestinal bile acid metabolism and hepatocyte pyroptosis (Hepatic fibrosis feces)

Hepatic fibrosis decreased feces bile acid level. Hepatic fibrosis increased serum bile acid. This result showed that hepatic fibrosis inhibited the excretion of bile acid in clinical patients. This result provided phenotype for hepatic fibrosis patients. Bile acid was important indexes for liver...

2023-03-17 | MTBLS6742 | MetaboLights
ProteomicsQuantitative Proteomics Reveals the role of Lysine 2-hydroxyisobutyrylation Pathway mediated by Tip60
Lysine 2-hydroxyisobutyrylation (Khib) is an evolutionary conserved and widespread protein posttranslational modification (PTM) that has diverse cellular functions. Recently, it has been demonstrated that Khib can be regulated by p300 and Tip60. Although the specific Khib substrates mediated by p300...
ORGANISM(S): Homo sapiens (Human) 
2022-02-22 | PXD029297 | Pride
Lysine 2-hydroxyisobutyrylation Tip60 Posttranslational modification Substrate Quantitative proteomics 
ProteomicsMass Spectrum-based Identification of direct-binding proteins of TAIII-probe
This experiment utilizes a technology platform based on the Ultimate 3000 nano ultra-high-performance liquid chromatography coupled with the Q Exactive Plus high-resolution mass spectrometer, combined with database search software, to perform qualitative (or relative quantitative) analysis of protei...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD060766 | Pride
ProteomicsHuman prion disease iTRAQ
Human prion diseases are fatal neurodegenerative disorders characterized by neuronal damage in brain. Protein S-nitrosylation, the covalent adduction of a NO to cysteine, plays a role in human brain biology, and brain dysfunction is a prominent feature of pPrion disease, yet the direct brain targets...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080756 | MassIVE
MetabolomicsGut microbiota ameliorates hepatic fibrosis through modulating intestinal bile acid metabolism and hepatocyte pyroptosis (Hepatic fibrosis serum)

Hepatic fibrosis decreased feces bile acid level. Hepatic fibrosis increased serum bile acid. This result showed that hepatic fibrosis inhibited the excretion of bile acid in clinical patients. This result provided phenotype for hepatic fibrosis patients. Bile acid was important indexes for liver...

2023-03-17 | MTBLS6732 | MetaboLights
UnknownSoftware Assisted Multi-Tiered Mass Spectrometry Identification of Compounds in Traditional Chinese Medicine: Dalbergia odorifera as an Example.
Not available
S-EPMC9000885 | biostudies-literature
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