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Proximity-dependent labelling (PL) methods are based on promiscuous labeling enzymes that produce reactive molecules that covalently bind neighbor proteins. Labeled proteins can be then purified and identified using affinity-purification coupled to mass spectrometry methods39. Proximity-dependent bi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-20 | PXD021770 | Pride
Proximity-dependent labelling (PL) methods are based on promiscuous labeling enzymes that produce reactive molecules that covalently bind neighbor proteins. Labeled proteins can be then purified and identified using affinity-purification coupled to mass spectrometry methods39. Proximity-dependent bi...
ORGANISM(S): Homo sapiens (Human) 
2021-09-20 | PXD021809 | Pride
Background & Aims: polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of multiple fluid-filled biliary cysts. Most PLD-causative genes participate in protein biogenesis and/or transport. Post-translational modifications (PTMs) are implicated in protein st...
ORGANISM(S): Homo sapiens (Human) 
2020-09-29 | PXD021139 | Pride
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a multi-organ damage that includes hepatic dysfunction, which has been observed in over 50% of COVID-19 patients. Liver injury in COVID-19 patients could be attributed to the cytopathic effects induced by the interation between the ...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD035263 | Pride
Photosynthetic capacity is the result of chloroplast biogenesis, but whether photosynthesis itself is required for chloroplast biogenesis has not been investigated. In this study we use 680nm red light to overexcite Photosystem II to disrupt photosynthesis in two conditional mutants (var2 and abc1k1...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-12-13 | PXD050814 | Pride
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