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N4-acetylcytidine (ac4C) is a ubiquitous RNA modification incorporated by cytidine acetyltransferase enzymes. Here, we report the biochemical characterization of Thermococcus kodakarensis Nat10 (TkNat10), an RNA acetyltransferase involved in archaeal thermotolerance. We demonstrate that TkNat10's ca...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-10-14 | MSV000096084 | MassIVE
Fate and behaviour of neural progenitor cells is tightly regulated during mammalian brain development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that are required for supplying energy and providing molecular building blocks to generate cells, govern progenitor function. H...
ORGANISM(S): Homo sapiens (Human) 
2022-01-14 | PXD026110 | Pride
Duchenne muscular dystrophy (DMD) is caused by genetic deficiency of dystrophin and characterized by massive structural and functional changes of skeletal muscle tissue, leading to terminal muscle failure. In this project, proteomics data from skeletal muscle of a genetically engineered DMD pig mode...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-02-05 | PXD014893 | Pride
Thermococcus kodakarensis is a thermophilic archaea used in this study to determine how changes in growth temperature affect protein expression. This organism was chosen, in part, due to the simplified proteome and potential protein stability gained when analyzing proteins at room temperature. Two t...
ORGANISM(S): Thermococcus kodakarensis KOD1 
2020-02-17 | PXD014814 | Pride
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